Table 2

Expression of MAPKsa and Src kinase in proliferative and secretory phase endometrium (benign group)

Statistical difference in the distribution of MAPKs and Src kinase in proliferative and secretory phase endometrium was calculated by the Mann-Whitney U test. Values shown are the mean absolute numbers obtained from Kodak image analysis of the Western blot signals. To determine the level of active kinase, the activated kinase value was divided by total kinase value and the value for β-actin. To determine the level of total kinase, the total kinase value was divided by the β-actin value. All values shown are ± SE of the mean.

VariableProliferative n = 26Secretory n = 12P
PERK/TERK/actin161 ± 55127 ± 430.5
TERK/actin0.7 ± 0.10.7 ± 0.20.4
PSrc/TSrc/actin25 ± 534 ± 90.4
TSrc/actin0.4 ± 0.10.4 ± 0.20.6
Pp38/Tp38/actin121 ± 20154 ± 240.3
Tp38/actin0.4 ± 0.10.6 ± 0.10.4
PJNK/TJNK/actin34 ± 1064 ± 230.2
TJNK/actin0.2 ± 0.030.2 ± 0.040.8
  • a MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase.