Table 2

Influence of mutation status on estrogen receptor (ER) status of grade 3, infiltrating ductal breast cancers

ClassClass descriptionNER+%Pa
1Noncarriers6546.2P1/2 < 0.0001
2 BRCA1 13815.2P1/3 = 0.065
3 BRCA2 3663.9P1/4 = 0.183
4Untested21754.8P2/3 < 0.0001
Total45642.3P2/4 < 0.0001
P3/4 = 0.276
  • a Pa/b represents the P for the t test between ER+% in classes a and b, therefore, P1/2 is the P value for the ttest comparing ER+% in noncarriers and BRCA1carriers.