Table 2.

Multivariable Cox regression analysis model for treatment-free survival

VariablenHR (95% CI)P
Model A
    Disease stage at diagnosis
        A1011*
        B254.0 (2.2-7.1)<0.001
        C92.6 (1.1-6.0)0.025
    ZAP-70 status
        Neg701*
        Pos652.1 (1.3-3.7)0.005
    T393C
        TT241*
        TC691.8 (0.8-4.4)0.167
        CC423.2 (1.3-7.8)0.010
Model B
    Disease stage at diagnosis
        A1011*
        B+C343.4 (2.0-5.6)<0.001
    ZAP-70 status
        Neg701*
        Pos652.1 (1.2-3.6)0.006
    T393C
        T+931*
        T−421.9 (1.1-3.3)0.013
  • NOTE: Nonsignificant variables (age, gender, and CD38 status) were stepwise removed from the model. The cutoff levels used in the analysis were as follows: age, 60 years; ZAP-70 or CD38 status, 20% positive cells. Model B consists of dichotomous variables.

  • * Reference.