Table 2.

Analysis of acquired mutation using the subcloning method

Patient no.Activating mutationTotal clonesActivating mutant clones
Wild-type clones
With T790MWithout T790MWith T790MWithout T790M
1Δ22181003
2Δ35405202
3Δ15105001
4Δ12101308
5Δ15133909
6Δ147117425
7Δ12045110
8L858R1801404
9L858R2001406
10L858R2005015
11L858R2151015
12Δ12311912
13L858R2108013
14Δ1197804