Table 4.

Changes of HSP70 and ILK in PBMC following treatment with 17-AAG at 6 and 25 hours after infusion on days 1 and 4, cycle 1

ProteinDay 1, 6 hPDay 1, 25 hPDay 4, 6 hPDay 4, 25 hP
HSP70176 (102-271)<0.01193.5 (104-326)<0.01127 (97-181)<0.01137.5 (115-190)<0.01
ILK78.5 (50-98)<0.0191 (51-162)0.1392 (43-119)0.0896.5 (74-157)0.91
  • NOTE: All data in table expressed as median % of baseline (range).