Table 6.

Lack of correlation between serum FR titer and inhibitory factor in posttreatment serum

Patient 2
Patient 9
Patient 10
FR titerIFN-γ responseFR titerIFN-γ responseFR titerIFN-γ response
Pretreatment31,100503,3401,0001,825
Posttreatment601,6503909001,550
  • NOTE: Serum FR titers were determined using ELISA. FR levels varied between patients, with patient 2 having low amounts and patient 10 high amounts both before and after treatment. Patient 9 experienced an increase in FR levels over the course of treatment. There was no consistent correlation between FR levels and inhibition of IFN-γ response against IGROV-1 tumor cells.