Table 2.

Results of multivariate COX regression analysis of overall survival among 510 irradiated rectal cancer patients

VariableHR95% CIP
Patient age<0.0001
    Below median1
    Above median1.031.01-1.05
Tumor-node-metastasis stage<0.0001
    I1
    II1.831.22-2.74
    III2.881.96-4.22
Circumferential margin<0.0001
    Negative1
    Positive1.941.41-2.67
Distance of tumor from the anal verge0.07
    10.1-15 cm1
    5.1-10 cm1.481.03-2.13
    ≤5 cm1.441.01-2.03
COX-2 expression0.009
    Low1
    High1.461.10-1.94
  • NOTE: A variable was included in the multivariate analysis if the P value in the univariate analysis was <0.10. Patients with missing data were excluded from the analysis.