Table 1.

Clinical characteristics of patients, distribution by class, and corresponding frequency of tumor take in mice

Patient characteristics
Tumor take, n (%)*
ParameterClassFrequency in the population (%)
Age<4811.23 (1/30)
<48 and >552813 (6/45)
>5560.820 (23/118)
Grade1193 (1/34)
24111 (8/75)
34030 (22/74)
HistologyILC14.28 (2/25)
IDC85.818 (28/152)
Estrogen receptor+704 (5/125)
3037 (19/52)
Axillary lymph-node+59.816 (23/134)
40.216 (10/64)
Tumor size (mm)<10533 (2/6)
>10 and <304813 (8/61)
>304722 (13/62)
Site of origin
Primary8315 (25/164)
Metastasis§1724 (8/34)
  • * Tumor take at the first passage.

  • The frequency of tumor take is statistically different between grade 3 and 1 or 2 and between ER-positive and ER-negative tumors, as calculated with the χ2 test.

  • Including subtypes such as mucin-producing carcinomas, basal-like carcinomas, and medullary carcinomas.

  • § Including the tumor tissue coming from axillary lymph node and omentum metastasis; ILC invasive lobular carcinoma, IDC, invasive ductal carcinoma.