Table 3.

Comparison between quantitative mRNA expression level of selected genes in nine original tumors and in their corresponding xenografts measured by quantitative RT-PCR

TumorsERαPRHER1HER2HER3HER4KI67Cyclin E1Cyclin E2
HBC-2*11111581,0351387745,6005574,810
HBCx-2010970462676,5144255,508
HBC-48772,6465516973,1055692,528
HBCx-432505,221460170128,0451,0945,580
HBC-564342114,3183571081,547473822
HBCx-59860178,6072,7381,19315,3262,35510,614
HBC-660577671961133,9729825,766
HBCx-63401,5001,4801921064,5071,8425,683
HBC-935237709873581203,1747822,740
HBCx-9201,3651,7621,0747511,4844,26615,412
HBC-1020726181,084458115,9133,5254,601
HBCx-1019006731,6221,119216,4053,1636,111
HBC-1358215120,8843381,4352,2025112,362
HBCx-1344432030,5959561,4681,1404585,031
HBC-128189188447372182,6784121,324
HBCx-126719542,2481,960457,0405375,285
HBC-162621,179985441901,9535701,765
HBCx-161103,1387,1199761247,0551,7303,281
  • NOTE: Numbers in bold correspond to positive or threshold levels of expression.

  • * Code of patients' tumor.

  • Corresponding xenograft.