Table 1.

Human myeloid immunosuppressive cell populations reported in current literature

PhenotypeMechanismTumor system/model
CD15+ (48)H2O2Metastatic adenocarcinomas of the pancreas, colon, and breast
CD15+, CD11b+, CD14 (50)ARG1RCC
Lin, DR (46)N/AHNSCC, non–small cell lung carcinoma, and breast cancer
DR, LinCD33+1*ROS/NORCC
  • Abbreviations: H2O2, hydrogen peroxide; HNSCC, squamous cell carcinoma of the head and neck; N/A, not applicable; ROS, reactive oxygen species.

  • * Dannull J, Su Z, Kuebler H, et al. Abrogation of immature myeloid cell induced immunosuppression, in preparation.