Table 3.

Median OS of Favorable and Unfavorable CTC and 30% and 50% PSA decrement groups in CRPC patients

Time PointCTC/7.5 mL
30% PSA Reduction from baseline (%)
50% PSA Reduction from baseline (%)
n≥5 (%)Median OS
Log-rank PHRN<30 (%)Median OS
Log-rank PHRn<50 (%)Median OS
Log-rank PHR
≥5≥30%<30%≥50%<50%
2-5 wk2033920.79.5<0.00014.52077117.215.20.36531.22078317.516.20.561.2
6-8 wk1633319.98.5<0.00013.61676022.811.50.00112.21677522.814.40.012.1
9-12 wk1493319.67.6<0.00015.31554618.510.20.00072.21555919.610.80.00062.3
13-20 wk1433119.86.7<0.00016.51424117.78.7<0.00012.91424617.79.90.00012.6