A. Correlative marker values at 3 time points
MarkerMedianRange
IL-6 (pg/mL)
    Day 15.91.4-56.9
    Day 158.41.7-112.4
    End of treatment11.91.7-62.7
IL-8 (pg/mL)
    Day 113.86.9-162.6
    Day 1514.39.0-217.6
    End of treatment11.99.7-20.3
Maspin* (fold change)
    Day 1−3.0−3.7 to 14.3
    Day 158.3−7.2 to 11.5
    End of treatment26.10.5-233.0
B. Correlative marker change from baseline
Marker
Median
Range
P
IL-6 (pg/mL)
    Day 15 change from baseline0.4−7.7-55.50.57
    End of treatment change from baseline4.50.3-16.00.03
IL-8 (pg/mL)
    Day 15 change from baseline3.0−49.5-55.00.73
    End of treatment change from baseline−1.8−39.2-2.90.31
Maspin (fold change)
    Day 15 change from baseline6.4−8.5-15.30.44
    End of treatment change from baseline28.7−13.8-236.00.09
  • * Values represent a fold change from a normalized measurement of internal control glyceraldehyde-3-phosphate dehydrogenase.