Table 1.

Discovery phase cohort tumor characteristics

n(%)
Invasive tumor size (mm), n = 46
    <55 (10.9)
    5-105 (10.9)
    10-2016 (34.8)
    20-5017 (37.0)
    >503 (6.5)
Lymph node status (no. positive nodes), n = 45*
    013 (28.9)
    1-323 (51.1)
    4-96 (13.3)
    >103 (6.7)
Histologic subtype, n = 46
    Ductal NOS41 (89.1)
    Lobular, pleomorphic1 (2.2)
    Cribriform1 (2.2)
    Mixed2 (4.3)
    Too small to type1 (2.2)
Grade, n = 43
    114 (32.6)
    219 (44.2)
    310 (23.3)
Lymphovascular invasion, n = 46
    Absent10 (21.7)
    Present36 (78.3)
% Overall tumor comprised by in situ carcinoma, n = 46
    <2517 (37.0)
    25-5015 (32.6)
    50-754 (8.7)
    >7510 (21.7)
Uniform/mixed DCIS morphology, n = 45§
    Uniform32 (69.6)
    Mixed14 (30.4)
  • Abbreviation: NOS, not otherwise specified.

  • * For 1 case, lymph node status not available.

  • Mixed subtypes included a mixture of NOS/tubular/cribriform and NOS/mucinous.

  • Three cases were too small to be graded.

  • § Excludes one sample from a tumor with lobular carcinoma in situ only.