Table 2.

Integrin β4 is associated with basal-like tumors

ClassificationIntegrin β4
P
Negative, n (%)Positive, n (%)
Luminal A
    Yes27/36 (75)9/36 (25)0.19
    No38/62 (61.29)24/62 (38.7)
Luminal B
    Yes22/29 (75.86)7/29 (24.1)0.245
    No43/69 (62.3)26/69 (37.7)
HER2+/ER
    Yes4/6 (66.7)2/6 (33.3)1
    No61/92 (66.3)31/92 (33.7)
Basal like
    Yes12/27 (44.4)15/27 (55.6)0.008
    No53/71 (74.65)18/71 (25.35)
  • NOTE: Classification of breast cancer subtypes was modified from Carey et al. (29), which used a panel of immunohistochemical markers to define subtypes obtained from microarray analysis. Luminal A tumors are ER+ and/or PR+, HER2; luminal B tumors are ER+ and/or PR+, HER2+; HER2+/ER tumors are ER, PR, and HER2+; and basal-like tumors are ER, PR, and HER2. The associations were calculated using χ2 analysis.