Table 2.

Clinical predictors for patient response to gefitinib

CharacteristicUnivariate analysis
Multivariate analysis
Responder (n, %)POdds ratio (95% CI)P
Age (y)
    <6011 (26)0.801
    ≥6010 (24)
Sex
    Male9 (19)0.127
    Female12 (33)
Stage
    IIIB1 (7)0.101
    IV20 (29)
Smoking history
    Never17 (41)0.001Reference0.008
    Ever4 (9)0.2 (0.0-0.6)
Histopathology
    Adenocarcinoma18 (35)0.009Reference0.183
    Other3 (9)0.4 (0.1-1.6)
Performance status
    0-112 (24)0.898
    2-39 (26)
Prior treatment
    No7 (44)0.054
    Yes14 (21)
SUV
    Low (<6.2)9 (53)0.003Reference0.018
    High (≥6.2)12 (18)0.2 (0.1-0.8)