Table 2.

GATA4/5 methylation frequencies in relation to clinicopathologic features of colorectal carcinoma tissue

GATA4GATA5
TNM stage
    I11/15 (73%)13/15 (87%)
    II21/32 (66%)21/29 (74%)
    III25/34 (74%)19/25 (76%)
    IV6/9 (67%)8/8 (100%)
Tumor Location
    Proximal32/41 (78%)31/36 (86%)
    Distal31/47 (66%)29/39 (74%)
Sex
    Male29/42 (69%)29/37 (78%)
    Female34/48 (71%)32/40 (80%)
Age at diagnosis*
    ≤ mean28/38 (74%)26/34 (76%)
    > mean35/52 (67%)35/43 (81%)
Histologic type
    Adenocarcinoma50/75 (67%)49/65 (75%)
    Mucinous carcinoma13/15 (87%)12/12 (100%)
Differentiation
    Poor6/8 (75%)6/7 (86%)
    Moderate52/71 (73%)47/59 (80%)
    Well5/11 (46%)8/11 (73%)
  • NOTE: No significant correlations were found.

  • * Individuals are divided into two groups: those with an age smaller than or equal to the mean age of the study population and those with an age higher than the mean age.