Table 2.

Univariate analysis of PFS in IgG MGUS training sample and IgA sample

Factor10-y PFS (%)
HR (95% CI)
P
IgGIgAIgGIgAIgGIgA
Age at diagnosis, y
    ≤7092921.001.00
    >7060602.85 (1.36-5.98)1.19 (0.47-3.01)0.0060.712
Gender
    F90901.001.00
    M88880.80 (0.46-1.43)0.57 (0.27-1.20)0.4590.142
MC, g/dL
    ≤1.594941.001.00
    >1.579794.34 (2.34-8.02)1.68 (0.82-3.46)<0.0010.155
Light-chain proteinuria
    Negative91911.001.00
    Positive66663.82 (1.94-7.54)2.68 (0.92-7.80)<0.0010.070
Polyclonal immunoglobulin levels, g/dL
    Normal92921.001.00
    Reduced72723.40 (1.87-6.18)3.11 (1.43-6.78)<0.0010.004
Serum Hb level, g/dL
    ≥12.589891.001.00
    <12.5 and >10.0871.72 (0.88-3.45)0.111
    Continuous (13.5)*0.720.001
    <12.5743.65 (1.78-7.50)<0.001
Period of recruitment
    1976-198583831.001.00
    1986-199591910.61 (0.32-1.15)0.72 (0.24-2.22)0.1280.572
    1996-200498980.70 (0.26-1.93)1.39 (0.44-4.36)0.4960.572
  • * Median value.