Table 4.

Grade 3 and 4 adverse events

Adverse eventAll patients (N = 29)
Grade 3 n (%)Grade 4 n (%)Grades 3-4 n (%)
Any11 (38)3 (10)14 (48)
Dyspnea1 (3)1 (3)2 (7)
Thrombocytopenia0 (0)2 (7)2 (7)
Abdominal pain1 (3)0 (0)1 (3)
Acute bronchitis1 (3)0 (0)1 (3)
Alkaline phosphatase increased1 (3)0 (0)1 (3)
ALT increased1 (3)0 (0)1 (3)
Anemia1 (3)0 (0)1 (3)
AST increased1 (3)0 (0)1 (3)
Chills1 (3)0 (0)1 (3)
Disease progression1 (3)0 (0)1 (3)
Fatigue1 (3)0 (0)1 (3)
Febrile neutropenia1 (3)0 (0)1 (3)
Gastrointestinal hemorrhage1 (3)0 (0)1 (3)
Hemoglobin decreased1 (3)0 (0)1 (3)
Hyperglycemia1 (3)0 (0)1 (3)
Neutropenia1 (3)0 (0)1 (3)
Pain1 (3)0 (0)1 (3)
Skin infection1 (3)0 (0)1 (3)
Syncope1 (3)0 (0)1 (3)

Abbreviations: ALT; alanine aminotransferase; AST, aspartate aminotransferase.