Table 1.

Interpretation of IHC staining on lung adenocarcinomas by three pathologists

Lung Adenocarcinoma (n = 153)
D5F3 antibodyALK1 antibody
Sensitivity (%)*10067
Specificity (%)*9997
Positive predictive value (%)9678
Negative predictive value (%)10095
κ statistic0.940.79
  • *Of the pathologists' IHC interpretation as positive staining in predicting an ALK rearrangement