Table 2.

Summary of samples analyzed for EGFR mutations based on specimen type

Sample adequacy based on specimen type (N = 153)
Sample typeTotal samplesSuccessfully profiled (%)Failures
Biopsies (including nondecalcified bone)9585 (89%)10 (11%)
Bone biopsies (decalcified)104 (40%)6 a (60%)
FNAs1411 (79%)3 (21%)
Fluid samples3424 (71%)10 (29%)
Pleural 2620 (77%)6 (23%)
Peritoneal 101 (100%)
Pericardial 21 (50%)1 (50%)
CSF 53 (60%)2 (40%)
  • aIncludes 1 biopsy partially analyzed (successful EGFR exon 19 and 21, failed T790M analysis).