Table 3.

Comparison of T790M mutation rate by type of testing method

Standard sequencingFragment analysisCombined standard and LNA-PCR/sequencing
Total cases tested694564
Positive cases (rate)34 (49%)24 (53%) *45 (70%) **
Negative cases (rate)35 (51%)21 (47%)19 (30%)

NOTE: Fisher's exact test for comparison to standard sequencing.