Table 1.

Patient characteristics and T790M prevalence

Characteristicsn (% total)% with T790MP
Gender
 Male33 (35)641
 Female60 (65)62
Race
 Asian17 (18)590.79
 Non-Asian76 (82)63
Smoking history
 Never smoker61 (66)610.66
 Former/current smoker32 (34)66
Stage
 IV at diagnosis71 (76)610.62
 Recurrent22 (24)68
EGFR-sensitizing mutation
 Exon 19 deletion70 (75)631
 Exon 21 point mutation23 (25)61
Initial TKI received
 Erlotinib64 (69)660.36
 Gefitinib29 (31)55
Line of treatment with TKI
 First-line/maintenance72 (77)640.13
 Second-line11 (12)36
 Third-line or later10 (11)80
Site of biopsy
 Lung/pleura67 (72)660.014
 Lymph node8 (9)75
 Othera18 (19)44

aLiver (n = 6), bone (n = 4), brain (n = 3), adrenal (n = 2), uterine cervix, skin, peritoneum.