Table 2

Main toxicities (worst per cycle) at each dose level expressed in number of cycles in which they occurred

Docetaxel mg/m2R101933 mg b.i.d.No. pts/ cycleNeutropenia CTC gradeaNeutropenic feverVomiting CTC gradeMucositis CTC gradeFatigue CTC gradeDLTc
01234012340123012
602003/11452110111650
752003/181163717116210620
1002003/725275112140
1003006/23112316420121732112744
  • a NCI CTC.