Table 4

LOH at 9p21 and p16 methylation by degree of dysplasia

Mild dysplasiaModerate dysplasiaSevere dysplasiaTotalFisher’s exact test
9p21 LOH2 (100%)8 (66%)7 (64%)17 (68%)P = 0.83
9p21 retention0448
Methylation1 (33%)11 (79%)9 (82%)21 (75%)P = 0.24
No methylation2327