Table 3

Cox proportional hazard regression analysis for subgroups of patients

VariablePFSOS
HRa95% CIbPHRa95% CIbP
Stage III/IV
 HK10 unadjusted2.071.13–3.780.0182.351.11–5.010.026
 HK10 adjustedc1.981.07–3.680.0312.120.96–4.710.057
Stage I/II
 HK10 unadjusted0.690.14–3.280.641.730.17–16.90.63
 HK10 adjustedc1.140.23–5.460.862.430.24–24.70.45
Tumor grade III
 HK10 unadjusted1.910.93–3.160.0832.261.01–5.080.047
 HK10 adjustedd0.940.48–1.810.851.090.48–2.450.83
Tumor grade I/II
 HK10 unadjusted3.851.12–13.20.0313.580.80–16.10.094
 HK10 adjustedd2.010.52–7.680.322.580.52–12.80.24
Suboptimal Debulking
 HK10 unadjusted1.710.74–3.070.251.610.71–3.630.26
 HK10 adjustede1.340.63–2.810.441.160.49–2.700.72
Optimal Debulking
 HK10 unadjusted0.740.25–2.170.591.360.25–7.480.71
 HK10 adjustede0.720.22–2.280.581.260.20–7.780.79
  • a HR estimated from Cox proportional hazards regression model.

  • b Confidence interval of the estimated HR.

  • c Multivariate models were adjusted for tumor grade, residual tumor, histologic type, and age.

  • d Multivariate models were adjusted for stage of disease, residual tumor, histologic type, and age.

  • e Multivariate models were adjusted for stage of disease, tumor grade, histologic type, and age.