Table 4

Criteria for morphological grading of endomyocardial biopsy specimens (Modified Billingham Scale; Ref. 26 )

GradeVacuolesaMyofibrillar dropoutaNecrosisa
0.5<400
1.04–10<30
1.5>103–5<2
2.06–82–5
  • a Average number of abnormal muscle fibers/grid based on an examination of a minimum of six grids obtained from six blocks.