Table 3

p53, EGFR, mdm2, and Ki-67, and status for STS GBMs

Individual results are given by case number. Results based on immunohistochemistry are scored as “+” or “−”, except for Ki-67, which is expressed as percentage of positive cells. For the p53 gene, the mutation is represented by showing the mutated codon and amino acid change.

Casep53 proteinp53 geneEGFRmdm2Ki-67
1WTc++40.0
2+ND19.6
3+WT+7.9
4+WT+19.0
5+ND18.6
6+WT+62.1
7ND+53.7
8WT++15.4
9WT+69.9
10WT+28.3
11ND16.1
12+WT+35.5
13+WT+38.2
14ND+23.1
15ND35.8
16ND+26.6
17+ND+50.1
18ND+27.8
19+codon 273 arg→his+12.7
20+codon 132 lys→thr++17.8
21+ND16.1
22WT++39.1
23+ND+59.4
24+ND29.1
25ND+39.0
26+ND+14.7
27WT+33.6
28+WT++21.4
29+WT+20.6
30+WT++58.0
31ND++41.0
32+WT+15.4
33+codon 273 arg→his26.6
34ND+55.3
35+ND+23.9
36+ND+50.2
37+codon 152 pro→leu+46.2
38+codon 175 arg→his30.2
39codon 237 met→ile37.9
40+WT+58.1
41+WT++26.9
42ND+22.5
43ND+6.2
44+codon 273 arg→cys+7.3
45WT++17.9
46ND++51.6
47ND10.8
48+G-C splice site intron 4+44.1
  • a WT, wild type; ND, not determined because of unamplifiable DNA and/or unavailable slides.