Table 1

Patient and tumor characteristics

PatientAge (yrs)SitePostsurgery stagePostsurgery histologyDay radiotherapy startedSection type pathology HPV/HLAaHPV typingb
166MunichIIbSquamous80FSquamousHPV-16
240MunichIbSquamousFNot interpretable
367FreiburgIbSquamousNR
458MunichIIbSquamous79NR
536MunichIIaSquamousWSquamous
633MunichIbSquamousWNo lesion
744MunichIIbMucinous-AC72FAC+
849MunichIIbAdenocarcinoma−14, 82WSquamous
955FreiburgIbAdenocarcinomaNR
1048CardiffIbSquamousWSquamousHPV-18
1147MunichIIbSquamous69WSquamousHPV-16
1239BonnIbSquamous88FCIN
1337MunichIbSquamousWSquamous
14c47JenaIIaSquamous31FSquamousHPV-16
1549JenaIbSquamousFCINHPV-58
1634CardiffIbSquamousWSquamous
17d47CardiffIbSquamousWSquamous
1834ManchesterIbSquamousFSquamousHPV-16/39
1965JenaIbSquamousFCIN
2043JenaIbSquamousFSquamousHPV-18
2147JenaIbSquamousNR
2247JenaIaAdenocarcinomaFWarty
23c41JenaIIbSquamousFSquamousHPV-16
2442ManchesterIbSquamous112FSquamousHPV-16
2541CardiffIbSquamousWNo lesion+/−
2644JenaIbAdenocarcinomaFNo lesion
2732ManchesterIbSquamousFNo lesion
2836CardiffCINIIICINIIIWCINIIIHPV-16
2947MunichUterine CaMucinous Adenocarcinoma90NR
  • a Sections used for analysis of the HPV (and HLA) expression were different from those used to assign pathology after surgery (F, frozen sections; W, wax-embedded; NR, not received).

  • b HPV typing positive (+) but not identified, negative (−), or uncertain (+/−).

  • c Patient received only one vaccination due to radiotherapy (14) or progressive disease (23).

  • d The first vaccination failed to take, but the second vaccination resulted in a strong local response.