Table 4

Characteristics of squamous cell carcinoma of the tonsil by presence or absence of HPVa

CharacteristicHuman papillomavirusbP
Present (n = 24)Absent (n = 28)
Tumor, n (%)0.038
 T19 (37.5)4 (14.3)
 T27 (29.2)9 (32.1)
 T34 (16.7)3 (10.7)
 T43 (12.5)10 (35.7)
 Unknown1 (4.2)2 (7.1)
Nodal involvement, n (%)0.88
 NX0 (0)4 (14.3)
 N04 (16.7)3 (10.7)
 N12 (8.3)2 (7.1)
 N217 (70.8)16 (57.1)
 N31 (4.2)1 (3.6)
 Unknown0 (0)2 (7.1)
Stage, n (%)0.95
 I2 (8.3)2 (7.1)
 II1 (4.2)0 (0)
 III1 (4.2)3 (10.7)
 IV20 (83.3)21 (75.0)
 Unknown0 (0)2 (7.1)
Tumor size, cm0.015
 Median2.23.5
 Range1.0–5.51.0–8.3
Histologic differentiation, n (%)0.22
 Grade 10 (0)0 (0)
 Grade 23 (12.5)3 (10.7)
 Grade 321 (87.5)21 (75.0)
 Grade 40 (0)4 (14.3)
Keratinization, n (%)0.10
 Yes10 (41.7)18 (64.3)
 No13 (54.2)9 (32.1)
 Unknown1 (4.2)1 (3.6)
  • a Patients with unknown characteristics were ignored in the assessment of statistical significance.

  • b Values are number (percentage) unless otherwise indicated.