Table 4

Hematological toxicity of CHS 828 (possible/probable relationship to CHS 828)a

CTC grade≤50 mg (n = 8)51–100 mg (n = 25)101–150 mg (n = 15)151–200 mg (n = 1)Total (n = 49)Percentage of all cycles
Thrombocytopenia47%
 111204
 205409
 3045110
Lymphocytopenia29%
 101001
 202002
 3065011
Anemia18%
 100101
 202507
 301001
Leukopenia (WBC)10%
 110001
 210203
 300101
  • a n = total number of evaluable cycles. If more than one occurrence per patient in the same cycle, AE is recorded only once with maximum severity.