Table 5

Prognostic factors in ESCC patients treated by neoadjuvant chemotherapy and surgery by Cox proportional hazard model

Univariate analysisMultivariate analysis
Risk ratio95% CIPRisk ratio95% CIP
Depth of invasion
 T31
 T41.3180.673–2.5790.4204N.D.
LN status
 NO11
N1 and/or M1 lymph2.6001.145–5.9040.02242.8151.185–6.6910.0191
Clinical response
 CR + PR11
 SD + PD2.6571.435–4.9230.00192.2811.199–4.3400.0119
Histological response
 Grade 1b–211
 Grade 0–1a2.3511.085–5.0960.03031.4820.651–3.3730.3489
MLH1 expression
 High11
 Low1.8881.022–3.4880.04252.0201.146–4.2310.0178
P53 expression
 Negative1
 Positive1.6170.790–3.3090.1881N.D.
  • N.D., not done; CI, confidence interval.