Table 4

Organ systems involved for attributable grade 3 or 4 toxicities

Organ systemGrade 3Grade 4Total
Blood/bone marrow142539
Cardiovascular (Arrhythmia)101
Cardiovascular (General)112
Constitutional symptoms808
Dermatology/skin101
Gastrointestinal707
Infection/febrile neutropenia9110
Liver101
Metabolic/laboratory314
Neurology909
Pain505