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Clinical Cancer Research
Clinical Cancer Research

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About the Cover

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The Cover

The alternative reading frame protein p14ARF is a small basic tumor suppressor expressed in the nucleus and nucleoli in response to oncogene activation or after loss of normal cell cycle control. The image shows scattered p14ARF positive cells (brown) by immunohistochemistry in a case of cervical carcinoma in situ counterstained with hematoxylin and eosin. In addition to nuclear staining some diffuse cytoplasmic reactivity can be seen. For details, see J.L. Wang et al., in this issue.

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Clinical Cancer Research: 10 (7)
April 2004
Volume 10, Issue 7
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Issue Highlights

  • Predictive Significance of the Alterations of p16INK4A, p14ARF, p53, and Proliferating Cell Nuclear Antigen Expression in the Progression of Cervical Cancer
  • Bayesian Pharmacokinetically Guided Dosing of Paclitaxel in Patients with Non-Small Cell Lung Cancer
  • Inhibition of Src Tyrosine Kinase Impairs Inherent and Acquired Gemcitabine Resistance in Human Pancreatic Adenocarcinoma Cells
  • Second Round Results of the Finnish Population-Based Prostate Cancer Screening Trial
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Copyright © 2019 by the American Association for Cancer Research.

Clinical Cancer Research
eISSN: 1557-3265
ISSN: 1078-0432

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