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Table of Contents

Editorials

  • Editorials
    Updated Methods for Reporting Clinical Trials
    William N. Hait
    Clin Cancer Res October 1 2005 11 (19) 6753-6754; DOI:10.1158/1078-0432.CCR-05-1768

  • Editorials
    A Reporter's Advice to Medical Researchers
    Daniel Q. Haney
    Clin Cancer Res October 1 2005 11 (19) 6755-6756; DOI:10.1158/1078-0432.CCR-05-1476

The Biology Behind

  • The Biology Behind
    Optimizing Prostate Cancer Treatment by Combining Local Radiation Therapy with Systemic Vaccination
    Howard L. Kaufman and Chaitanya R. Divgi
    Clin Cancer Res October 1 2005 11 (19) 6757-6762; DOI:10.1158/1078-0432.CCR-05-0644

  • The Biology Behind
    Obesity and Prostate Cancer: A Growing Problem
    Stephen J. Freedland
    Clin Cancer Res October 1 2005 11 (19) 6763-6766; DOI:10.1158/1078-0432.CCR-05-1305

Report from the FDA

  • Report from the FDA
    Food and Drug Administration Drug Approval Summary: Temozolomide Plus Radiation Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme
    Martin H. Cohen, John R. Johnson and Richard Pazdur
    Clin Cancer Res October 1 2005 11 (19) 6767-6771; DOI:10.1158/1078-0432.CCR-05-0722

Human Cancer Biology

  • Human Cancer Biology
    Morphologic Instability and Cancer Invasion
    Vittorio Cristini, Hermann B. Frieboes, Robert Gatenby, Sergio Caserta, Mauro Ferrari and John Sinek
    Clin Cancer Res October 1 2005 11 (19) 6772-6779; DOI:10.1158/1078-0432.CCR-05-0852

  • Human Cancer Biology
    The Septin-Binding Protein Anillin Is Overexpressed in Diverse Human Tumors
    Peter A. Hall, Christopher B. Todd, Paula L. Hyland, Simon S. McDade, Heike Grabsch, Mit Dattani, Kenneth J. Hillan and S.E. Hilary Russell
    Clin Cancer Res October 1 2005 11 (19) 6780-6786; DOI:10.1158/1078-0432.CCR-05-0997

  • Human Cancer Biology
    Myelomastocytic Leukemia: Evidence for the Origin of Mast Cells from the Leukemic Clone and Eradication by Allogeneic Stem Cell Transplantation
    Wolfgang R. Sperr, Johannes Drach, Alexander W. Hauswirth, Jutta Ackermann, Margit Mitterbauer, Gerlinde Mitterbauer, Manuela Foedinger, Christa Fonatsch, Ingrid Simonitsch-Klupp, Peter Kalhs and Peter Valent
    Clin Cancer Res October 1 2005 11 (19) 6787-6792; DOI:10.1158/1078-0432.CCR-05-1064

  • Human Cancer Biology
    Tumor Necrosis Factor α and Adiponectin in Bone Marrow Interstitial Fluid from Patients with Acute Myeloid Leukemia Inhibit Normal Hematopoiesis
    Per Ole Iversen and Helge Wiig
    Clin Cancer Res October 1 2005 11 (19) 6793-6799; DOI:10.1158/1078-0432.CCR-05-1033

  • Human Cancer Biology
    Clinicopathologic and Biological Significance of Kallikrein 6 Overexpression in Human Gastric Cancer
    Hisashi Nagahara, Koshi Mimori, Tohru Utsunomiya, Graham F. Barnard, Masaichi Ohira, Kosei Hirakawa and Masaki Mori
    Clin Cancer Res October 1 2005 11 (19) 6800-6806; DOI:10.1158/1078-0432.CCR-05-0943

  • Human Cancer Biology
    The Role of Cyclooxygenase-2 in Mediating the Effects of Histamine on Cell Proliferation and Vascular Endothelial Growth Factor Production in Colorectal Cancer
    Fabio Cianchi, Camillo Cortesini, Nicola Schiavone, Federico Perna, Lucia Magnelli, Elena Fanti, Daniele Bani, Luca Messerini, Valentina Fabbroni, Giuliano Perigli, Sergio Capaccioli and Emanuela Masini
    Clin Cancer Res October 1 2005 11 (19) 6807-6815; DOI:10.1158/1078-0432.CCR-05-0675

  • Human Cancer Biology
    Clinicopathologic Significance of the Mutations of the Epidermal Growth Factor Receptor Gene in Patients with Non–Small Cell Lung Cancer
    Yoshio Tomizawa, Hironobu Iijima, Noriaki Sunaga, Koji Sato, Atsushi Takise, Yoshimi Otani, Shigefumi Tanaka, Tatsuo Suga, Ryusei Saito, Tamotsu Ishizuka, Kunio Dobashi, John D. Minna, Takashi Nakajima and Masatomo Mori
    Clin Cancer Res October 1 2005 11 (19) 6816-6822; DOI:10.1158/1078-0432.CCR-05-0441

  • Human Cancer Biology
    Molecular Alterations in Primary Prostate Cancer after Androgen Ablation Therapy
    Carolyn J.M. Best, John W. Gillespie, Yajun Yi, Gadisetti V.R. Chandramouli, Mark A. Perlmutter, Yvonne Gathright, Heidi S. Erickson, Lauren Georgevich, Michael A. Tangrea, Paul H. Duray, Sergio González, Alfredo Velasco, W. Marston Linehan, Robert J. Matusik, Douglas K. Price, William D. Figg, Michael R. Emmert-Buck and Rodrigo F. Chuaqui
    Clin Cancer Res October 1 2005 11 (19) 6823-6834; DOI:10.1158/1078-0432.CCR-05-0585

  • Human Cancer Biology
    PRL-3 Phosphatase Is Implicated in Ovarian Cancer Growth
    Federica Polato, Annamaria Codegoni, Robert Fruscio, Patrizia Perego, Costantino Mangioni, Saurabh Saha, Alberto Bardelli and Massimo Broggini
    Clin Cancer Res October 1 2005 11 (19) 6835-6839; DOI:10.1158/1078-0432.CCR-04-2357

  • Human Cancer Biology
    p53 Codon 72 and MDM2 SNP309 Polymorphisms and Age of Colorectal Cancer Onset in Lynch Syndrome
    Kaisa Sotamaa, Sandya Liyanarachchi, Jukka-Pekka Mecklin, Heikki Järvinen, Lauri A. Aaltonen, Päivi Peltomäki and Albert de la Chapelle
    Clin Cancer Res October 1 2005 11 (19) 6840-6844; DOI:10.1158/1078-0432.CCR-05-1139

  • Human Cancer Biology
    Reduced Cisplatin Sensitivity of Head and Neck Squamous Cell Carcinoma Cell Lines Correlates with Mutations Affecting the COOH-Terminal Nuclear Localization Signal of p53
    Robert Mandic, Chantal J. Schamberger, Julia F. Müller, Matthias Geyer, Li Zhu, Thomas E. Carey, Reidar Grénman, Anja A. Dünne and Jochen A. Werner
    Clin Cancer Res October 1 2005 11 (19) 6845-6852; DOI:10.1158/1078-0432.CCR-05-0378

  • Human Cancer Biology
    High Frequency of Hereditary Colorectal Cancer in Newfoundland Likely Involves Novel Susceptibility Genes
    Michael O. Woods, Angela J. Hyde, Fiona K. Curtis, Susan Stuckless, Jane S. Green, Aaron F. Pollett, J. Desmond Robb, Roger C. Green, Marina E. Croitoru, Amanda Careen, Jason A.W. Chaulk, Jegan Jegathesan, John R. McLaughlin, Steven S. Gallinger, H. Banfield Younghusband, Bharati V. Bapat and Patrick S. Parfrey
    Clin Cancer Res October 1 2005 11 (19) 6853-6861; DOI:10.1158/1078-0432.CCR-05-0726

Imaging, Diagnosis, Prognosis

  • Imaging, Diagnosis, Prognosis
    Evaluation of a Panel of Molecular Markers for the Diagnosis of Malignant Serous Effusions
    Karine Passebosc-Faure, Guorong Li, Claude Lambert, Michèle Cottier, Anne Gentil-Perret, Pierre Fournel, Maurice Pérol and Christian Genin
    Clin Cancer Res October 1 2005 11 (19) 6862-6867; DOI:10.1158/1078-0432.CCR-05-0043

  • Imaging, Diagnosis, Prognosis
    Thomsen-Friedenreich and Tn Antigens in Nipple Fluid: Carbohydrate Biomarkers for Breast Cancer Detection
    Senthil R. Kumar, Edward R. Sauter, Thomas P. Quinn and Susan L. Deutscher
    Clin Cancer Res October 1 2005 11 (19) 6868-6871; DOI:10.1158/1078-0432.CCR-05-0146

  • Imaging, Diagnosis, Prognosis
    Annexin A8 Is Up-Regulated During Mouse Mammary Gland Involution and Predicts Poor Survival in Breast Cancer
    Torsten Stein, Karen N. Price, Joanna S. Morris, Victoria J. Heath, Roderick K. Ferrier, Alexandra K. Bell, Marie-Anne Pringle, René Villadsen, Ole W. Petersen, Guido Sauter, Gareth Bryson, Elizabeth A. Mallon and Barry A. Gusterson
    Clin Cancer Res October 1 2005 11 (19) 6872-6879; DOI:10.1158/1078-0432.CCR-05-0547

  • Imaging, Diagnosis, Prognosis
    Identification of Overexpression and Amplification of ABCF2 in Clear Cell Ovarian Adenocarcinomas by cDNA Microarray Analyses
    Hiroshi Tsuda, Yoichi M. Ito, Yasuo Ohashi, Kwong-Kwok Wong, Yasunori Hashiguchi, William R. Welch, Ross S. Berkowitz, Michael J. Birrer and Samuel C. Mok
    Clin Cancer Res October 1 2005 11 (19) 6880-6888; DOI:10.1158/1078-0432.CCR-05-0751

Cancer Therapy: Clinical

  • Cancer Therapy: Clinical
    Obesity, Weight Gain, and Risk of Biochemical Failure among Prostate Cancer Patients following Prostatectomy
    Sara S. Strom, Xuemei Wang, Curtis A. Pettaway, Christopher J. Logothetis, Yuko Yamamura, Kim-Anh Do, Richard J. Babaian and Patricia Troncoso
    Clin Cancer Res October 1 2005 11 (19) 6889-6894; DOI:10.1158/1078-0432.CCR-04-1977

  • Cancer Therapy: Clinical
    Gemcitabine Radiosensitization after High-Dose Samarium for Osteoblastic Osteosarcoma
    Peter M. Anderson, Gregory A. Wiseman, Linda Erlandson, Vilmarie Rodriguez, Barbara Trotz, Stephen A. Dubansky and Karen Albritton
    Clin Cancer Res October 1 2005 11 (19) 6895-6900; DOI:10.1158/1078-0432.CCR-05-0628

  • Cancer Therapy: Clinical
    Carboxylesterase Isoform 2 mRNA Expression in Peripheral Blood Mononuclear Cells Is a Predictive Marker of the Irinotecan to SN38 Activation Step in Colorectal Cancer Patients
    Erika Cecchin, Giuseppe Corona, Sara Masier, Paola Biason, Giulio Cattarossi, Sergio Frustaci, Angela Buonadonna, Annamaria Colussi and Giuseppe Toffoli
    Clin Cancer Res October 1 2005 11 (19) 6901-6907; DOI:10.1158/1078-0432.CCR-05-0602

  • Cancer Therapy: Clinical
    Phase I and Pharmacologic Study of PKI166, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients with Advanced Solid Malignancies
    Ronald Hoekstra, Herlinde Dumez, Ferry A.L.M. Eskens, Ate van der Gaast, Andre S.T. Planting, Gerda de Heus, Kurt C. Sizer, Christina Ravera, Sujata Vaidyanathan, Corazon Bucana, Isaiah J. Fidler, Allan T. van Oosterom and Jaap Verweij
    Clin Cancer Res October 1 2005 11 (19) 6908-6915; DOI:10.1158/1078-0432.CCR-05-0720

  • Cancer Therapy: Clinical
    Responses to Human CD40 Ligand/Human Interleukin-2 Autologous Cell Vaccine in Patients with B-Cell Chronic Lymphocytic Leukemia
    Ettore Biagi, Raphael Rousseau, Eric Yvon, Mary Schwartz, Gianpietro Dotti, Aaron Foster, Diana Havlik-Cooper, Bambi Grilley, Adrian Gee, Kelty Baker, George Carrum, Lawrence Rice, Michael Andreeff, Uday Popat and Malcolm Brenner
    Clin Cancer Res October 1 2005 11 (19) 6916-6923; DOI:10.1158/1078-0432.CCR-05-0484

Cancer Therapy: Preclinical

  • Cancer Therapy: Preclinical
    Dasatinib (BMS-354825) Tyrosine Kinase Inhibitor Suppresses Invasion and Induces Cell Cycle Arrest and Apoptosis of Head and Neck Squamous Cell Carcinoma and Non–Small Cell Lung Cancer Cells
    Faye M. Johnson, Babita Saigal, Moshe Talpaz and Nicholas J. Donato
    Clin Cancer Res October 1 2005 11 (19) 6924-6932; DOI:10.1158/1078-0432.CCR-05-0757

  • Cancer Therapy: Preclinical
    Identification of Peptide Vaccine Candidates for Prostate Cancer Patients with HLA-A3 Supertype Alleles
    Satoko Matsueda, Hiroko Takedatsu, Akihisa Yao, Masahiro Tanaka, Masanori Noguchi, Kyogo Itoh and Mamoru Harada
    Clin Cancer Res October 1 2005 11 (19) 6933-6943; DOI:10.1158/1078-0432.CCR-05-0682

  • Cancer Therapy: Preclinical
    Determination of Doxorubicin Levels in Whole Tumor and Tumor Nuclei in Murine Breast Cancer Tumors
    Kimberley M. Laginha, Sylvia Verwoert, Gregory J.R. Charrois and Theresa M. Allen
    Clin Cancer Res October 1 2005 11 (19) 6944-6949; DOI:10.1158/1078-0432.CCR-05-0343

  • Cancer Therapy: Preclinical
    In vivo Evaluation of Ixabepilone (BMS247550), A Novel Epothilone B Derivative, against Pediatric Cancer Models
    Jennifer K. Peterson, Chandra Tucker, Edward Favours, Pamela J. Cheshire, Jeremy Creech, Catherine A. Billups, Richard Smykla, Francis Y.F. Lee and Peter J. Houghton
    Clin Cancer Res October 1 2005 11 (19) 6950-6958; DOI:10.1158/1078-0432.CCR-05-0740

  • Cancer Therapy: Preclinical
    Absence of Adverse Effects in Cynomolgus Macaques Treated with CNTO 95, a Fully Human Anti-αv Integrin Monoclonal Antibody, Despite Widespread Tissue Binding
    Pauline L. Martin, Qun Jiao, Joel Cornacoff, William Hall, Bradley Saville, Jeffrey A. Nemeth, Allen Schantz, Marielena Mata, Haishan Jang, Adedigbo A. Fasanmade, Lisa Anderson, Martin A. Graham, Hugh M. Davis and George Treacy
    Clin Cancer Res October 1 2005 11 (19) 6959-6965; DOI:10.1158/1078-0432.CCR-04-2623

  • Cancer Therapy: Preclinical
    Vascular Endothelial Growth Factor Trap Combined with Paclitaxel Strikingly Inhibits Tumor and Ascites, Prolonging Survival in a Human Ovarian Cancer Model
    Limin Hu, Judith Hofmann, Jocelyn Holash, George D. Yancopoulos, Anil K. Sood and Robert B. Jaffe
    Clin Cancer Res October 1 2005 11 (19) 6966-6971; DOI:10.1158/1078-0432.CCR-05-0910

  • Cancer Therapy: Preclinical
    Effect of the St. John's Wort Constituent Hyperforin on Docetaxel Metabolism by Human Hepatocyte Cultures
    Bernard J. Komoroski, Robert A. Parise, Merrill J. Egorin, Stephen C. Strom and Raman Venkataramanan
    Clin Cancer Res October 1 2005 11 (19) 6972-6979; DOI:10.1158/1078-0432.CCR-04-2488

  • Cancer Therapy: Preclinical
    Radiation Sensitivity of Human Carcinoma Cells Transfected with Small Interfering RNA Targeted against Cyclooxygenase-2
    Sanjeewani T. Palayoor, Moly J. Arayankalayil, Azadeh Shoaibi and C. Norman Coleman
    Clin Cancer Res October 1 2005 11 (19) 6980-6986; DOI:10.1158/1078-0432.CCR-05-0326

  • Cancer Therapy: Preclinical
    Combined Abl Inhibitor Therapy for Minimizing Drug Resistance in Chronic Myeloid Leukemia: Src/Abl Inhibitors Are Compatible with Imatinib
    Thomas O'Hare, Denise K. Walters, Eric P. Stoffregen, Daniel W. Sherbenou, Michael C. Heinrich, Michael W.N. Deininger and Brian J. Druker
    Clin Cancer Res October 1 2005 11 (19) 6987-6993; DOI:10.1158/1078-0432.CCR-05-0622

  • Cancer Therapy: Preclinical
    Curcumin Suppresses Growth of Head and Neck Squamous Cell Carcinoma
    Maria M. LoTempio, Mysore S. Veena, Helen L. Steele, Bharathi Ramamurthy, Tirunelveli S. Ramalingam, Alen N. Cohen, Rita Chakrabarti, Eri S. Srivatsan and Marilene B. Wang
    Clin Cancer Res October 1 2005 11 (19) 6994-7002; DOI:10.1158/1078-0432.CCR-05-0301

  • Cancer Therapy: Preclinical
    Differential Metastasis Inhibition by Clinically Relevant Levels of Heparins—Correlation with Selectin Inhibition, Not Antithrombotic Activity
    Jennifer L. Stevenson, Sharon H. Choi and Ajit Varki
    Clin Cancer Res October 1 2005 11 (19) 7003-7011; DOI:10.1158/1078-0432.CCR-05-1131

  • Cancer Therapy: Preclinical
    Bladder Cancer Stage and Outcome by Array-Based Comparative Genomic Hybridization
    Ekaterini Blaveri, Jeremy L. Brewer, Ritu Roydasgupta, Jane Fridlyand, Sandy DeVries, Theresa Koppie, Sunanda Pejavar, Kshama Mehta, Peter Carroll, Jeff P. Simko and Frederic M. Waldman
    Clin Cancer Res October 1 2005 11 (19) 7012-7022; DOI:10.1158/1078-0432.CCR-05-0177

  • Cancer Therapy: Preclinical
    Pharmacokinetic-Pharmacodynamic Relationships for the Heat Shock Protein 90 Molecular Chaperone Inhibitor 17-Allylamino, 17-Demethoxygeldanamycin in Human Ovarian Cancer Xenograft Models
    Udai Banerji, Michael Walton, Florence Raynaud, Rachel Grimshaw, Lloyd Kelland, Melani Valenti, Ian Judson and Paul Workman
    Clin Cancer Res October 1 2005 11 (19) 7023-7032; DOI:10.1158/1078-0432.CCR-05-0518

Cancer Prevention

  • Cancer Prevention
    Reversal of Hypermethylation and Reactivation of p16INK4a, RARβ, and MGMT Genes by Genistein and Other Isoflavones from Soy
    Ming Zhu Fang, Dapeng Chen, Yi Sun, Zhe Jin, Judith K. Christman and Chung S. Yang
    Clin Cancer Res October 1 2005 11 (19) 7033-7041; DOI:10.1158/1078-0432.CCR-05-0406

Letters to the Editor

  • Letters to the Editor
    PIK3CA Mutations in Ovarian Cancer
    Ian G. Campbell, Sarah E. Russell and Wayne A. Phillips
    Clin Cancer Res October 1 2005 11 (19) 7042-7043; DOI:10.1158/1078-0432.CCR-05-1024

  • Letters to the Editor
    Mammaglobin as Molecular Marker of Breast Cancer (Micro)Metastases
    Paul N. Span and Fred C.G.J. Sweep
    Clin Cancer Res October 1 2005 11 (19) 7043-7044; DOI:10.1158/1078-0432.CCR-05-1378

Introduction

  • Introduction
    Introduction to the Tenth Conference on Cancer Therapy with Antibodies and Immunoconjugates
    David M. Goldenberg
    Clin Cancer Res October 1 2005 11 (19) 7045s-7046s; DOI:10.1158/1078-0432.CCR-1004-0025

Experimental Studies

  • Experimental Studies
    Mechanisms of Cell Sensitization to α Radioimmunotherapy by Doxorubicin or Paclitaxel in Multiple Myeloma Cell Lines
    Stephane Supiot, Sebastien Gouard, Josiane Charrier, Christos Apostolidis, Jean-Francois Chatal, Jacques Barbet, François Davodeau and Michel Cherel
    Clin Cancer Res October 1 2005 11 (19) 7047s-7052s; DOI:10.1158/1078-0432.CCR-1004-0021

  • Experimental Studies
    Radioimmunotherapy of Solid Tumors by Targeting Extra Domain B Fibronectin: Identification of the Best-Suited Radioimmunoconjugate
    Dietmar Berndorff, Sandra Borkowski, Stephanie Sieger, Axel Rother, Matthias Friebe, Francesca Viti, Christoph S. Hilger, John E. Cyr and Ludger M. Dinkelborg
    Clin Cancer Res October 1 2005 11 (19) 7053s-7063s; DOI:10.1158/1078-0432.CCR-1004-0015

  • Experimental Studies
    Nuclear Imaging of Met-Expressing Human and Canine Cancer Xenografts with Radiolabeled Monoclonal Antibodies (MetSeekTM)
    Rick V. Hay, Brian Cao, R. Scot Skinner, Yanli Su, Ping Zhao, Margaret F. Gustafson, Chao-Nan Qian, Bin T. Teh, Beatrice S. Knudsen, James H. Resau, Shuren Shen, David J. Waters, Milton D. Gross and George F. Vande Woude
    Clin Cancer Res October 1 2005 11 (19) 7064s-7069s; DOI:10.1158/1078-0432.CCR-1004-0014

  • Experimental Studies
    Fractionated Locoregional Low-Dose Radioimmunotherapy Improves Survival in a Mouse Model of Diffuse-Type Gastric Cancer Using a 213Bi-Conjugated Monoclonal Antibody
    Stefanie Bloechl, Roswitha Beck, Christof Seidl, Alfred Morgenstern, Markus Schwaiger and Reingard Senekowitsch-Schmidtke
    Clin Cancer Res October 1 2005 11 (19) 7070s-7074s; DOI:10.1158/1078-0432.CCR-1004-0017

  • Experimental Studies
    Direct Antilymphoma Effects on Human Lymphoma Cells of Monotherapy and Combination Therapy with CD20 and HLA-DR Antibodies and 90Y-Labeled HLA-DR Antibodies
    Gerald L. DeNardo, Evan Tobin, Kaylund Chan, Bonnie M. Bradt and Sally J. DeNardo
    Clin Cancer Res October 1 2005 11 (19) 7075s-7079s; DOI:10.1158/1078-0432.CCR-1004-0008

  • Experimental Studies
    Enhanced Efficacy of Radioimmunotherapy with 90Y-CHX-A″-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478
    Fook T. Lee, Angela J. Mountain, Marcus P. Kelly, Cathrine Hall, Angela Rigopoulos, Terrance G. Johns, Fiona E. Smyth, Martin W. Brechbiel, Edouard C. Nice, Antony W. Burgess and Andrew M. Scott
    Clin Cancer Res October 1 2005 11 (19) 7080s-7086s; DOI:10.1158/1078-0432.CCR-1004-0019

  • Experimental Studies
    Development of Tumor Targeting Bioprobes (111In-Chimeric L6 Monoclonal Antibody Nanoparticles) for Alternating Magnetic Field Cancer Therapy
    Sally J. DeNardo, Gerald L. DeNardo, Laird A. Miers, Arutselvan Natarajan, Alan R. Foreman, Cordula Gruettner, Grete N. Adamson and Robert Ivkov
    Clin Cancer Res October 1 2005 11 (19) 7087s-7092s; DOI:10.1158/1078-0432.CCR-1004-0022

  • Experimental Studies
    Application of High Amplitude Alternating Magnetic Fields for Heat Induction of Nanoparticles Localized in Cancer
    Robert Ivkov, Sally J. DeNardo, Wolfgang Daum, Allan R. Foreman, Robert C. Goldstein, Valentin S. Nemkov and Gerald L. DeNardo
    Clin Cancer Res October 1 2005 11 (19) 7093s-7103s; DOI:10.1158/1078-0432.CCR-1004-0016

  • Experimental Studies
    Determining Maximal Tolerable Dose of the Monoclonal Antibody BR96 Labeled with 90Y or 177Lu in Rats: Establishment of a Syngeneic Tumor Model to Evaluate Means to Improve Radioimmunotherapy
    Linda Mårtensson, Zhongmin Wang, Rune Nilsson, Tomas Ohlsson, Peter Senter, Hans-Olov Sjögren, Sven-Erik Strand and Jan Tennvall
    Clin Cancer Res October 1 2005 11 (19) 7104s-7108s; DOI:10.1158/1078-0432.CCR-1004-0004

Pretargeting Studies

  • Pretargeting Studies
    Improving the Delivery of Radionuclides for Imaging and Therapy of Cancer Using Pretargeting Methods
    Robert M. Sharkey, Habibe Karacay, Thomas M. Cardillo, Chien-Hsing Chang, William J. McBride, Edmund A. Rossi, Ivan D. Horak and David M. Goldenberg
    Clin Cancer Res October 1 2005 11 (19) 7109s-7121s; DOI:10.1158/1078-0432.CCR-1004-0009

  • Pretargeting Studies
    Pretargeting of Carcinoembryonic Antigen–Expressing Cancers with a Trivalent Bispecific Fusion Protein Produced in Myeloma Cells
    Edmund A. Rossi, Chien-Hsing Chang, Michele J. Losman, Robert M. Sharkey, Habibe Karacay, William McBride, Thomas M. Cardillo, Hans J. Hansen, Zhengxing Qu, Ivan D. Horak and David M. Goldenberg
    Clin Cancer Res October 1 2005 11 (19) 7122s-7129s; DOI:10.1158/1078-0432.CCR-1004-0020

  • Pretargeting Studies
    Pretargeting of Carcinoembryonic Antigen–Expressing Tumors with a Biologically Produced Bispecific Anticarcinoembryonic Antigen × Anti-Indium–Labeled Diethylenetriaminepentaacetic Acid Antibody
    Frank G. van Schaijk, Egbert Oosterwijk, Annemieke C. Soede, Matthias Broekema, Cathelijne Frielink, William J. McBride, David M. Goldenberg, Frans H.M. Corstens and Otto C. Boerman
    Clin Cancer Res October 1 2005 11 (19) 7130s-7136s; DOI:10.1158/1078-0432.CCR-1004-0006

  • Pretargeting Studies
    Improved Tumor Targeting by Combined Use of Two Antitenascin Antibodies
    Fiorella Petronzelli, Angela Pelliccia, Anna Maria Anastasi, Valeria D'Alessio, Claudio Albertoni, Antonio Rosi, Barbara Leoni, Clara De Angelis, Giovanni Paganelli, Giovanna Palombo, Maria Dani, Paolo Carminati and Rita De Santis
    Clin Cancer Res October 1 2005 11 (19) 7137s-7145s; DOI:10.1158/1078-0432.CCR-1004-0007

Clinical Studies

  • Clinical Studies
    Full-Dose 90Y Ibritumomab Tiuxetan Therapy Is Safe in Patients with Prior Myeloablative Chemotherapy
    Samuel A. Jacobs, Nicholas Vidnovic, Judith Joyce, Barry McCook, Frank Torok and Norbert Avril
    Clin Cancer Res October 1 2005 11 (19) 7146s-7150s; DOI:10.1158/1078-0432.CCR-1004-0003

  • Clinical Studies
    Management of Central Nervous System Lymphomas Using Monoclonal Antibodies: Challenges and Opportunities
    Eric T. Wong
    Clin Cancer Res October 1 2005 11 (19) 7151s-7157s; DOI:10.1158/1078-0432.CCR-1004-0002

  • Clinical Studies
    Does Paclitaxel (Taxol) Given after 111In-Labeled Monoclonal Antibodies Increase Tumor-Cumulated Activity in Epithelial Cancers?
    Laird Miers, Kathleen Lamborn, Aina Yuan, Carol Richman, Arutselvan Natarajan, Sally DeNardo and Gerald DeNardo
    Clin Cancer Res October 1 2005 11 (19) 7158s-7163s; DOI:10.1158/1078-0432.CCR-1004-0012

  • Clinical Studies
    Preliminary Results of the Safety of Immunotherapy with Gemtuzumab Ozogamicin following Reduced Intensity Allogeneic Stem Cell Transplant in Children with CD33+ Acute Myeloid Leukemia
    Elizabeth Roman, Erin Cooney, Lauren Harrison, Olga Militano, Karen Wolownik, Ria Hawks, Sandi Foley, Prakash Satwani, Elif Unal, Monica Bhatia, Brigid Bradley, Gustavo Del Toro, Diane George, James Garvin, Carmella van de Ven and Mitchell S. Cairo
    Clin Cancer Res October 1 2005 11 (19) 7164s-7170s; DOI:10.1158/1078-0432.CCR-1004-0018

  • Clinical Studies
    Blood Pharmacokinetics of Various Monoclonal Antibodies Labeled with a New Trifunctional Chelating Reagent for Simultaneous Conjugation with 1,4,7,10-Tetraazacyclododecane-N,N′,N″,N‴-Tetraacetic Acid and Biotin before Radiolabeling
    Zhongmin Wang, Linda Mårtensson, Rune Nilsson, Pär-Ola Bendahl, Lars Lindgren, Tomas Ohlsson, Hans-Olov Sjögren, Sven-Erik Strand and Jan Tennvall
    Clin Cancer Res October 1 2005 11 (19) 7171s-7177s; DOI:10.1158/1078-0432.CCR-1004-0001

  • Clinical Studies
    Radioimmunotherapy with [131I]cG250 in Patients with Metastasized Renal Cell Cancer: Dosimetric Analysis and Immunologic Response
    Adrienne H. Brouwers, Wilhelmina C.A.M. Buijs, Peter F.A. Mulders, Pieter H.M. de Mulder, Wim J.M. van den Broek, Carola Mala, Egbert Oosterwijk, Otto C. Boerman, Frans H.M. Corstens and Wim J.G. Oyen
    Clin Cancer Res October 1 2005 11 (19) 7178s-7186s; DOI:10.1158/1078-0432.CCR-1004-0010

  • Clinical Studies
    Enhancement of the Therapeutic Index: From Nonmyeloablative and Myeloablative toward Pretargeted Radioimmunotherapy for Metastatic Prostate Cancer
    Sally J. DeNardo, Carol M. Richman, Huguette Albrecht, Patricia A. Burke, Arut Natarajan, Aina Yuan, Jeff P. Gregg, R.T. O'Donnell and Gerald L. DeNardo
    Clin Cancer Res October 1 2005 11 (19) 7187s-7194s; DOI:10.1158/1078-0432.CCR-1004-0013

  • Clinical Studies
    Radioimmunotherapy of Prostate Cancer Using 90Y- and 177Lu-Labeled J591 Monoclonal Antibodies: Effect of Multiple Treatments on Myelotoxicity
    Shankar Vallabhajosula, Stanley J. Goldsmith, Lale Kostakoglu, Mathew I. Milowsky, David M. Nanus and Neil H. Bander
    Clin Cancer Res October 1 2005 11 (19) 7195s-7200s; DOI:10.1158/1078-0432.CCR-1004-0023

  • Clinical Studies
    Concluding Remarks: Tenth Conference on Cancer Therapy with Antibodies and Immunoconjugates
    Sally J. DeNardo
    Clin Cancer Res October 1 2005 11 (19) 7201s-7202s; DOI:10.1158/1078-0432.CCR-1004-0024

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Clinical Cancer Research: 11 (19)
October 2005
Volume 11, Issue 19
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Issue Highlights

  • The Septin-Binding Protein Anillin Is Overexpressed in Diverse Human Tumors
  • Thomsen-Friedenreich and Tn Antigens in Nipple Fluid: Carbohydrate Biomarkers for Breast Cancer Detection
  • Dasatinib (BMS-354825) Tyrosine Kinase Inhibitor Suppresses Invasion and Induces Cell Cycle Arrest and Apoptosis of Head and Neck Squamous Cell Carcinoma and Non–Small Cell Lung Cancer Cells

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  • scRNA-seq Analysis of Gastric Cancer TME
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  • PDAC and GATA6 Expression
  • Rucaparib in mCRPC with a Non-BRCA DDR Gene Alteration
  • AR Gene Rearrangements in Prostate Cancer
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Clinical Cancer Research
eISSN: 1557-3265
ISSN: 1078-0432

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