Clinical Cancer Research: 11 (19)

Editorials

Editorials

Updated Methods for Reporting Clinical Trials

William N. Hait

Clin Cancer Res October 1 2005 11 (19) 6753-6754; DOI:10.1158/1078-0432.CCR-05-1768
Editorials

A Reporter's Advice to Medical Researchers

Daniel Q. Haney

Clin Cancer Res October 1 2005 11 (19) 6755-6756; DOI:10.1158/1078-0432.CCR-05-1476

The Biology Behind

The Biology Behind

Optimizing Prostate Cancer Treatment by Combining Local Radiation Therapy with Systemic Vaccination

Howard L. Kaufman and Chaitanya R. Divgi

Clin Cancer Res October 1 2005 11 (19) 6757-6762; DOI:10.1158/1078-0432.CCR-05-0644
The Biology Behind

Obesity and Prostate Cancer: A Growing Problem

Stephen J. Freedland

Clin Cancer Res October 1 2005 11 (19) 6763-6766; DOI:10.1158/1078-0432.CCR-05-1305

Report from the FDA

Report from the FDA

Food and Drug Administration Drug Approval Summary: Temozolomide Plus Radiation Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme

Martin H. Cohen, John R. Johnson and Richard Pazdur

Clin Cancer Res October 1 2005 11 (19) 6767-6771; DOI:10.1158/1078-0432.CCR-05-0722

Human Cancer Biology

Human Cancer Biology

Morphologic Instability and Cancer Invasion

Vittorio Cristini, Hermann B. Frieboes, Robert Gatenby, Sergio Caserta, Mauro Ferrari and John Sinek

Clin Cancer Res October 1 2005 11 (19) 6772-6779; DOI:10.1158/1078-0432.CCR-05-0852
Human Cancer Biology

The Septin-Binding Protein Anillin Is Overexpressed in Diverse Human Tumors

Peter A. Hall, Christopher B. Todd, Paula L. Hyland, Simon S. McDade, Heike Grabsch, Mit Dattani, Kenneth J. Hillan and S.E. Hilary Russell

Clin Cancer Res October 1 2005 11 (19) 6780-6786; DOI:10.1158/1078-0432.CCR-05-0997
Human Cancer Biology

Myelomastocytic Leukemia: Evidence for the Origin of Mast Cells from the Leukemic Clone and Eradication by Allogeneic Stem Cell Transplantation

Wolfgang R. Sperr, Johannes Drach, Alexander W. Hauswirth, Jutta Ackermann, Margit Mitterbauer, Gerlinde Mitterbauer, Manuela Foedinger, Christa Fonatsch, Ingrid Simonitsch-Klupp, Peter Kalhs and Peter Valent

Clin Cancer Res October 1 2005 11 (19) 6787-6792; DOI:10.1158/1078-0432.CCR-05-1064
Human Cancer Biology

Tumor Necrosis Factor α and Adiponectin in Bone Marrow Interstitial Fluid from Patients with Acute Myeloid Leukemia Inhibit Normal Hematopoiesis

Per Ole Iversen and Helge Wiig

Clin Cancer Res October 1 2005 11 (19) 6793-6799; DOI:10.1158/1078-0432.CCR-05-1033
Human Cancer Biology

Clinicopathologic and Biological Significance of Kallikrein 6 Overexpression in Human Gastric Cancer

Hisashi Nagahara, Koshi Mimori, Tohru Utsunomiya, Graham F. Barnard, Masaichi Ohira, Kosei Hirakawa and Masaki Mori

Clin Cancer Res October 1 2005 11 (19) 6800-6806; DOI:10.1158/1078-0432.CCR-05-0943
Human Cancer Biology

The Role of Cyclooxygenase-2 in Mediating the Effects of Histamine on Cell Proliferation and Vascular Endothelial Growth Factor Production in Colorectal Cancer

Fabio Cianchi, Camillo Cortesini, Nicola Schiavone, Federico Perna, Lucia Magnelli, Elena Fanti, Daniele Bani, Luca Messerini, Valentina Fabbroni, Giuliano Perigli, Sergio Capaccioli and Emanuela Masini

Clin Cancer Res October 1 2005 11 (19) 6807-6815; DOI:10.1158/1078-0432.CCR-05-0675
Human Cancer Biology

Clinicopathologic Significance of the Mutations of the Epidermal Growth Factor Receptor Gene in Patients with Non–Small Cell Lung Cancer

Yoshio Tomizawa, Hironobu Iijima, Noriaki Sunaga, Koji Sato, Atsushi Takise, Yoshimi Otani, Shigefumi Tanaka, Tatsuo Suga, Ryusei Saito, Tamotsu Ishizuka, Kunio Dobashi, John D. Minna, Takashi Nakajima and Masatomo Mori

Clin Cancer Res October 1 2005 11 (19) 6816-6822; DOI:10.1158/1078-0432.CCR-05-0441
Human Cancer Biology

Molecular Alterations in Primary Prostate Cancer after Androgen Ablation Therapy

Carolyn J.M. Best, John W. Gillespie, Yajun Yi, Gadisetti V.R. Chandramouli, Mark A. Perlmutter, Yvonne Gathright, Heidi S. Erickson, Lauren Georgevich, Michael A. Tangrea, Paul H. Duray, Sergio González, Alfredo Velasco, W. Marston Linehan, Robert J. Matusik, Douglas K. Price, William D. Figg, Michael R. Emmert-Buck and Rodrigo F. Chuaqui

Clin Cancer Res October 1 2005 11 (19) 6823-6834; DOI:10.1158/1078-0432.CCR-05-0585
Human Cancer Biology

PRL-3 Phosphatase Is Implicated in Ovarian Cancer Growth

Federica Polato, Annamaria Codegoni, Robert Fruscio, Patrizia Perego, Costantino Mangioni, Saurabh Saha, Alberto Bardelli and Massimo Broggini

Clin Cancer Res October 1 2005 11 (19) 6835-6839; DOI:10.1158/1078-0432.CCR-04-2357
Human Cancer Biology

p53 Codon 72 and MDM2 SNP309 Polymorphisms and Age of Colorectal Cancer Onset in Lynch Syndrome

Kaisa Sotamaa, Sandya Liyanarachchi, Jukka-Pekka Mecklin, Heikki Järvinen, Lauri A. Aaltonen, Päivi Peltomäki and Albert de la Chapelle

Clin Cancer Res October 1 2005 11 (19) 6840-6844; DOI:10.1158/1078-0432.CCR-05-1139
Human Cancer Biology

Reduced Cisplatin Sensitivity of Head and Neck Squamous Cell Carcinoma Cell Lines Correlates with Mutations Affecting the COOH-Terminal Nuclear Localization Signal of p53

Robert Mandic, Chantal J. Schamberger, Julia F. Müller, Matthias Geyer, Li Zhu, Thomas E. Carey, Reidar Grénman, Anja A. Dünne and Jochen A. Werner

Clin Cancer Res October 1 2005 11 (19) 6845-6852; DOI:10.1158/1078-0432.CCR-05-0378
Human Cancer Biology

High Frequency of Hereditary Colorectal Cancer in Newfoundland Likely Involves Novel Susceptibility Genes

Michael O. Woods, Angela J. Hyde, Fiona K. Curtis, Susan Stuckless, Jane S. Green, Aaron F. Pollett, J. Desmond Robb, Roger C. Green, Marina E. Croitoru, Amanda Careen, Jason A.W. Chaulk, Jegan Jegathesan, John R. McLaughlin, Steven S. Gallinger, H. Banfield Younghusband, Bharati V. Bapat and Patrick S. Parfrey

Clin Cancer Res October 1 2005 11 (19) 6853-6861; DOI:10.1158/1078-0432.CCR-05-0726

Imaging, Diagnosis, Prognosis

Imaging, Diagnosis, Prognosis

Evaluation of a Panel of Molecular Markers for the Diagnosis of Malignant Serous Effusions

Karine Passebosc-Faure, Guorong Li, Claude Lambert, Michèle Cottier, Anne Gentil-Perret, Pierre Fournel, Maurice Pérol and Christian Genin

Clin Cancer Res October 1 2005 11 (19) 6862-6867; DOI:10.1158/1078-0432.CCR-05-0043
Imaging, Diagnosis, Prognosis

Thomsen-Friedenreich and Tn Antigens in Nipple Fluid: Carbohydrate Biomarkers for Breast Cancer Detection

Senthil R. Kumar, Edward R. Sauter, Thomas P. Quinn and Susan L. Deutscher

Clin Cancer Res October 1 2005 11 (19) 6868-6871; DOI:10.1158/1078-0432.CCR-05-0146
Imaging, Diagnosis, Prognosis

Annexin A8 Is Up-Regulated During Mouse Mammary Gland Involution and Predicts Poor Survival in Breast Cancer

Torsten Stein, Karen N. Price, Joanna S. Morris, Victoria J. Heath, Roderick K. Ferrier, Alexandra K. Bell, Marie-Anne Pringle, René Villadsen, Ole W. Petersen, Guido Sauter, Gareth Bryson, Elizabeth A. Mallon and Barry A. Gusterson

Clin Cancer Res October 1 2005 11 (19) 6872-6879; DOI:10.1158/1078-0432.CCR-05-0547
Imaging, Diagnosis, Prognosis

Identification of Overexpression and Amplification of ABCF2 in Clear Cell Ovarian Adenocarcinomas by cDNA Microarray Analyses

Hiroshi Tsuda, Yoichi M. Ito, Yasuo Ohashi, Kwong-Kwok Wong, Yasunori Hashiguchi, William R. Welch, Ross S. Berkowitz, Michael J. Birrer and Samuel C. Mok

Clin Cancer Res October 1 2005 11 (19) 6880-6888; DOI:10.1158/1078-0432.CCR-05-0751

Cancer Therapy: Clinical

Cancer Therapy: Clinical

Obesity, Weight Gain, and Risk of Biochemical Failure among Prostate Cancer Patients following Prostatectomy

Sara S. Strom, Xuemei Wang, Curtis A. Pettaway, Christopher J. Logothetis, Yuko Yamamura, Kim-Anh Do, Richard J. Babaian and Patricia Troncoso

Clin Cancer Res October 1 2005 11 (19) 6889-6894; DOI:10.1158/1078-0432.CCR-04-1977
Cancer Therapy: Clinical

Gemcitabine Radiosensitization after High-Dose Samarium for Osteoblastic Osteosarcoma

Peter M. Anderson, Gregory A. Wiseman, Linda Erlandson, Vilmarie Rodriguez, Barbara Trotz, Stephen A. Dubansky and Karen Albritton

Clin Cancer Res October 1 2005 11 (19) 6895-6900; DOI:10.1158/1078-0432.CCR-05-0628
Cancer Therapy: Clinical

Carboxylesterase Isoform 2 mRNA Expression in Peripheral Blood Mononuclear Cells Is a Predictive Marker of the Irinotecan to SN38 Activation Step in Colorectal Cancer Patients

Erika Cecchin, Giuseppe Corona, Sara Masier, Paola Biason, Giulio Cattarossi, Sergio Frustaci, Angela Buonadonna, Annamaria Colussi and Giuseppe Toffoli

Clin Cancer Res October 1 2005 11 (19) 6901-6907; DOI:10.1158/1078-0432.CCR-05-0602
Cancer Therapy: Clinical

Phase I and Pharmacologic Study of PKI166, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients with Advanced Solid Malignancies

Ronald Hoekstra, Herlinde Dumez, Ferry A.L.M. Eskens, Ate van der Gaast, Andre S.T. Planting, Gerda de Heus, Kurt C. Sizer, Christina Ravera, Sujata Vaidyanathan, Corazon Bucana, Isaiah J. Fidler, Allan T. van Oosterom and Jaap Verweij

Clin Cancer Res October 1 2005 11 (19) 6908-6915; DOI:10.1158/1078-0432.CCR-05-0720
Cancer Therapy: Clinical

Responses to Human CD40 Ligand/Human Interleukin-2 Autologous Cell Vaccine in Patients with B-Cell Chronic Lymphocytic Leukemia

Ettore Biagi, Raphael Rousseau, Eric Yvon, Mary Schwartz, Gianpietro Dotti, Aaron Foster, Diana Havlik-Cooper, Bambi Grilley, Adrian Gee, Kelty Baker, George Carrum, Lawrence Rice, Michael Andreeff, Uday Popat and Malcolm Brenner

Clin Cancer Res October 1 2005 11 (19) 6916-6923; DOI:10.1158/1078-0432.CCR-05-0484

Cancer Therapy: Preclinical

Cancer Therapy: Preclinical

Dasatinib (BMS-354825) Tyrosine Kinase Inhibitor Suppresses Invasion and Induces Cell Cycle Arrest and Apoptosis of Head and Neck Squamous Cell Carcinoma and Non–Small Cell Lung Cancer Cells

Faye M. Johnson, Babita Saigal, Moshe Talpaz and Nicholas J. Donato

Clin Cancer Res October 1 2005 11 (19) 6924-6932; DOI:10.1158/1078-0432.CCR-05-0757
Cancer Therapy: Preclinical

Identification of Peptide Vaccine Candidates for Prostate Cancer Patients with HLA-A3 Supertype Alleles

Satoko Matsueda, Hiroko Takedatsu, Akihisa Yao, Masahiro Tanaka, Masanori Noguchi, Kyogo Itoh and Mamoru Harada

Clin Cancer Res October 1 2005 11 (19) 6933-6943; DOI:10.1158/1078-0432.CCR-05-0682
Cancer Therapy: Preclinical

Determination of Doxorubicin Levels in Whole Tumor and Tumor Nuclei in Murine Breast Cancer Tumors

Kimberley M. Laginha, Sylvia Verwoert, Gregory J.R. Charrois and Theresa M. Allen

Clin Cancer Res October 1 2005 11 (19) 6944-6949; DOI:10.1158/1078-0432.CCR-05-0343
Cancer Therapy: Preclinical

In vivo Evaluation of Ixabepilone (BMS247550), A Novel Epothilone B Derivative, against Pediatric Cancer Models

Jennifer K. Peterson, Chandra Tucker, Edward Favours, Pamela J. Cheshire, Jeremy Creech, Catherine A. Billups, Richard Smykla, Francis Y.F. Lee and Peter J. Houghton

Clin Cancer Res October 1 2005 11 (19) 6950-6958; DOI:10.1158/1078-0432.CCR-05-0740
Cancer Therapy: Preclinical

Absence of Adverse Effects in Cynomolgus Macaques Treated with CNTO 95, a Fully Human Anti-αv Integrin Monoclonal Antibody, Despite Widespread Tissue Binding

Pauline L. Martin, Qun Jiao, Joel Cornacoff, William Hall, Bradley Saville, Jeffrey A. Nemeth, Allen Schantz, Marielena Mata, Haishan Jang, Adedigbo A. Fasanmade, Lisa Anderson, Martin A. Graham, Hugh M. Davis and George Treacy

Clin Cancer Res October 1 2005 11 (19) 6959-6965; DOI:10.1158/1078-0432.CCR-04-2623
Cancer Therapy: Preclinical

Vascular Endothelial Growth Factor Trap Combined with Paclitaxel Strikingly Inhibits Tumor and Ascites, Prolonging Survival in a Human Ovarian Cancer Model

Limin Hu, Judith Hofmann, Jocelyn Holash, George D. Yancopoulos, Anil K. Sood and Robert B. Jaffe

Clin Cancer Res October 1 2005 11 (19) 6966-6971; DOI:10.1158/1078-0432.CCR-05-0910
Cancer Therapy: Preclinical

Effect of the St. John's Wort Constituent Hyperforin on Docetaxel Metabolism by Human Hepatocyte Cultures

Bernard J. Komoroski, Robert A. Parise, Merrill J. Egorin, Stephen C. Strom and Raman Venkataramanan

Clin Cancer Res October 1 2005 11 (19) 6972-6979; DOI:10.1158/1078-0432.CCR-04-2488
Cancer Therapy: Preclinical

Radiation Sensitivity of Human Carcinoma Cells Transfected with Small Interfering RNA Targeted against Cyclooxygenase-2

Sanjeewani T. Palayoor, Moly J. Arayankalayil, Azadeh Shoaibi and C. Norman Coleman

Clin Cancer Res October 1 2005 11 (19) 6980-6986; DOI:10.1158/1078-0432.CCR-05-0326
Cancer Therapy: Preclinical

Combined Abl Inhibitor Therapy for Minimizing Drug Resistance in Chronic Myeloid Leukemia: Src/Abl Inhibitors Are Compatible with Imatinib

Thomas O'Hare, Denise K. Walters, Eric P. Stoffregen, Daniel W. Sherbenou, Michael C. Heinrich, Michael W.N. Deininger and Brian J. Druker

Clin Cancer Res October 1 2005 11 (19) 6987-6993; DOI:10.1158/1078-0432.CCR-05-0622
Cancer Therapy: Preclinical

Curcumin Suppresses Growth of Head and Neck Squamous Cell Carcinoma

Maria M. LoTempio, Mysore S. Veena, Helen L. Steele, Bharathi Ramamurthy, Tirunelveli S. Ramalingam, Alen N. Cohen, Rita Chakrabarti, Eri S. Srivatsan and Marilene B. Wang

Clin Cancer Res October 1 2005 11 (19) 6994-7002; DOI:10.1158/1078-0432.CCR-05-0301
Cancer Therapy: Preclinical

Differential Metastasis Inhibition by Clinically Relevant Levels of Heparins—Correlation with Selectin Inhibition, Not Antithrombotic Activity

Jennifer L. Stevenson, Sharon H. Choi and Ajit Varki

Clin Cancer Res October 1 2005 11 (19) 7003-7011; DOI:10.1158/1078-0432.CCR-05-1131
Cancer Therapy: Preclinical

Bladder Cancer Stage and Outcome by Array-Based Comparative Genomic Hybridization

Ekaterini Blaveri, Jeremy L. Brewer, Ritu Roydasgupta, Jane Fridlyand, Sandy DeVries, Theresa Koppie, Sunanda Pejavar, Kshama Mehta, Peter Carroll, Jeff P. Simko and Frederic M. Waldman

Clin Cancer Res October 1 2005 11 (19) 7012-7022; DOI:10.1158/1078-0432.CCR-05-0177
Cancer Therapy: Preclinical

Pharmacokinetic-Pharmacodynamic Relationships for the Heat Shock Protein 90 Molecular Chaperone Inhibitor 17-Allylamino, 17-Demethoxygeldanamycin in Human Ovarian Cancer Xenograft Models

Udai Banerji, Michael Walton, Florence Raynaud, Rachel Grimshaw, Lloyd Kelland, Melani Valenti, Ian Judson and Paul Workman

Clin Cancer Res October 1 2005 11 (19) 7023-7032; DOI:10.1158/1078-0432.CCR-05-0518

Cancer Prevention

Cancer Prevention

Reversal of Hypermethylation and Reactivation of p16^INK4a, RARβ, and MGMT Genes by Genistein and Other Isoflavones from Soy

Ming Zhu Fang, Dapeng Chen, Yi Sun, Zhe Jin, Judith K. Christman and Chung S. Yang

Clin Cancer Res October 1 2005 11 (19) 7033-7041; DOI:10.1158/1078-0432.CCR-05-0406

Letters to the Editor

Letters to the Editor

PIK3CA Mutations in Ovarian Cancer

Ian G. Campbell, Sarah E. Russell and Wayne A. Phillips

Clin Cancer Res October 1 2005 11 (19) 7042-7043; DOI:10.1158/1078-0432.CCR-05-1024
Letters to the Editor

Mammaglobin as Molecular Marker of Breast Cancer (Micro)Metastases

Paul N. Span and Fred C.G.J. Sweep

Clin Cancer Res October 1 2005 11 (19) 7043-7044; DOI:10.1158/1078-0432.CCR-05-1378

Introduction

Introduction

Introduction to the Tenth Conference on Cancer Therapy with Antibodies and Immunoconjugates

David M. Goldenberg

Clin Cancer Res October 1 2005 11 (19) 7045s-7046s; DOI:10.1158/1078-0432.CCR-1004-0025

Experimental Studies

Experimental Studies

Mechanisms of Cell Sensitization to α Radioimmunotherapy by Doxorubicin or Paclitaxel in Multiple Myeloma Cell Lines

Stephane Supiot, Sebastien Gouard, Josiane Charrier, Christos Apostolidis, Jean-Francois Chatal, Jacques Barbet, François Davodeau and Michel Cherel

Clin Cancer Res October 1 2005 11 (19) 7047s-7052s; DOI:10.1158/1078-0432.CCR-1004-0021
Experimental Studies

Radioimmunotherapy of Solid Tumors by Targeting Extra Domain B Fibronectin: Identification of the Best-Suited Radioimmunoconjugate

Dietmar Berndorff, Sandra Borkowski, Stephanie Sieger, Axel Rother, Matthias Friebe, Francesca Viti, Christoph S. Hilger, John E. Cyr and Ludger M. Dinkelborg

Clin Cancer Res October 1 2005 11 (19) 7053s-7063s; DOI:10.1158/1078-0432.CCR-1004-0015
Experimental Studies

Nuclear Imaging of Met-Expressing Human and Canine Cancer Xenografts with Radiolabeled Monoclonal Antibodies (MetSeek^TM)

Rick V. Hay, Brian Cao, R. Scot Skinner, Yanli Su, Ping Zhao, Margaret F. Gustafson, Chao-Nan Qian, Bin T. Teh, Beatrice S. Knudsen, James H. Resau, Shuren Shen, David J. Waters, Milton D. Gross and George F. Vande Woude

Clin Cancer Res October 1 2005 11 (19) 7064s-7069s; DOI:10.1158/1078-0432.CCR-1004-0014
Experimental Studies

Fractionated Locoregional Low-Dose Radioimmunotherapy Improves Survival in a Mouse Model of Diffuse-Type Gastric Cancer Using a ²¹³Bi-Conjugated Monoclonal Antibody

Stefanie Bloechl, Roswitha Beck, Christof Seidl, Alfred Morgenstern, Markus Schwaiger and Reingard Senekowitsch-Schmidtke

Clin Cancer Res October 1 2005 11 (19) 7070s-7074s; DOI:10.1158/1078-0432.CCR-1004-0017
Experimental Studies

Direct Antilymphoma Effects on Human Lymphoma Cells of Monotherapy and Combination Therapy with CD20 and HLA-DR Antibodies and ⁹⁰Y-Labeled HLA-DR Antibodies

Gerald L. DeNardo, Evan Tobin, Kaylund Chan, Bonnie M. Bradt and Sally J. DeNardo

Clin Cancer Res October 1 2005 11 (19) 7075s-7079s; DOI:10.1158/1078-0432.CCR-1004-0008
Experimental Studies

Enhanced Efficacy of Radioimmunotherapy with ⁹⁰Y-CHX-A″-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478

Fook T. Lee, Angela J. Mountain, Marcus P. Kelly, Cathrine Hall, Angela Rigopoulos, Terrance G. Johns, Fiona E. Smyth, Martin W. Brechbiel, Edouard C. Nice, Antony W. Burgess and Andrew M. Scott

Clin Cancer Res October 1 2005 11 (19) 7080s-7086s; DOI:10.1158/1078-0432.CCR-1004-0019
Experimental Studies

Development of Tumor Targeting Bioprobes (¹¹¹In-Chimeric L6 Monoclonal Antibody Nanoparticles) for Alternating Magnetic Field Cancer Therapy

Sally J. DeNardo, Gerald L. DeNardo, Laird A. Miers, Arutselvan Natarajan, Alan R. Foreman, Cordula Gruettner, Grete N. Adamson and Robert Ivkov

Clin Cancer Res October 1 2005 11 (19) 7087s-7092s; DOI:10.1158/1078-0432.CCR-1004-0022
Experimental Studies

Application of High Amplitude Alternating Magnetic Fields for Heat Induction of Nanoparticles Localized in Cancer

Robert Ivkov, Sally J. DeNardo, Wolfgang Daum, Allan R. Foreman, Robert C. Goldstein, Valentin S. Nemkov and Gerald L. DeNardo

Clin Cancer Res October 1 2005 11 (19) 7093s-7103s; DOI:10.1158/1078-0432.CCR-1004-0016
Experimental Studies

Determining Maximal Tolerable Dose of the Monoclonal Antibody BR96 Labeled with ⁹⁰Y or ¹⁷⁷Lu in Rats: Establishment of a Syngeneic Tumor Model to Evaluate Means to Improve Radioimmunotherapy

Linda Mårtensson, Zhongmin Wang, Rune Nilsson, Tomas Ohlsson, Peter Senter, Hans-Olov Sjögren, Sven-Erik Strand and Jan Tennvall

Clin Cancer Res October 1 2005 11 (19) 7104s-7108s; DOI:10.1158/1078-0432.CCR-1004-0004

Pretargeting Studies

Pretargeting Studies

Improving the Delivery of Radionuclides for Imaging and Therapy of Cancer Using Pretargeting Methods

Robert M. Sharkey, Habibe Karacay, Thomas M. Cardillo, Chien-Hsing Chang, William J. McBride, Edmund A. Rossi, Ivan D. Horak and David M. Goldenberg

Clin Cancer Res October 1 2005 11 (19) 7109s-7121s; DOI:10.1158/1078-0432.CCR-1004-0009
Pretargeting Studies

Pretargeting of Carcinoembryonic Antigen–Expressing Cancers with a Trivalent Bispecific Fusion Protein Produced in Myeloma Cells

Edmund A. Rossi, Chien-Hsing Chang, Michele J. Losman, Robert M. Sharkey, Habibe Karacay, William McBride, Thomas M. Cardillo, Hans J. Hansen, Zhengxing Qu, Ivan D. Horak and David M. Goldenberg

Clin Cancer Res October 1 2005 11 (19) 7122s-7129s; DOI:10.1158/1078-0432.CCR-1004-0020
Pretargeting Studies

Pretargeting of Carcinoembryonic Antigen–Expressing Tumors with a Biologically Produced Bispecific Anticarcinoembryonic Antigen × Anti-Indium–Labeled Diethylenetriaminepentaacetic Acid Antibody

Frank G. van Schaijk, Egbert Oosterwijk, Annemieke C. Soede, Matthias Broekema, Cathelijne Frielink, William J. McBride, David M. Goldenberg, Frans H.M. Corstens and Otto C. Boerman

Clin Cancer Res October 1 2005 11 (19) 7130s-7136s; DOI:10.1158/1078-0432.CCR-1004-0006
Pretargeting Studies

Improved Tumor Targeting by Combined Use of Two Antitenascin Antibodies

Fiorella Petronzelli, Angela Pelliccia, Anna Maria Anastasi, Valeria D'Alessio, Claudio Albertoni, Antonio Rosi, Barbara Leoni, Clara De Angelis, Giovanni Paganelli, Giovanna Palombo, Maria Dani, Paolo Carminati and Rita De Santis

Clin Cancer Res October 1 2005 11 (19) 7137s-7145s; DOI:10.1158/1078-0432.CCR-1004-0007

Clinical Studies

Clinical Studies

Full-Dose ⁹⁰Y Ibritumomab Tiuxetan Therapy Is Safe in Patients with Prior Myeloablative Chemotherapy

Samuel A. Jacobs, Nicholas Vidnovic, Judith Joyce, Barry McCook, Frank Torok and Norbert Avril

Clin Cancer Res October 1 2005 11 (19) 7146s-7150s; DOI:10.1158/1078-0432.CCR-1004-0003
Clinical Studies

Management of Central Nervous System Lymphomas Using Monoclonal Antibodies: Challenges and Opportunities

Eric T. Wong

Clin Cancer Res October 1 2005 11 (19) 7151s-7157s; DOI:10.1158/1078-0432.CCR-1004-0002
Clinical Studies

Does Paclitaxel (Taxol) Given after ¹¹¹In-Labeled Monoclonal Antibodies Increase Tumor-Cumulated Activity in Epithelial Cancers?

Laird Miers, Kathleen Lamborn, Aina Yuan, Carol Richman, Arutselvan Natarajan, Sally DeNardo and Gerald DeNardo

Clin Cancer Res October 1 2005 11 (19) 7158s-7163s; DOI:10.1158/1078-0432.CCR-1004-0012
Clinical Studies

Preliminary Results of the Safety of Immunotherapy with Gemtuzumab Ozogamicin following Reduced Intensity Allogeneic Stem Cell Transplant in Children with CD33⁺ Acute Myeloid Leukemia

Elizabeth Roman, Erin Cooney, Lauren Harrison, Olga Militano, Karen Wolownik, Ria Hawks, Sandi Foley, Prakash Satwani, Elif Unal, Monica Bhatia, Brigid Bradley, Gustavo Del Toro, Diane George, James Garvin, Carmella van de Ven and Mitchell S. Cairo

Clin Cancer Res October 1 2005 11 (19) 7164s-7170s; DOI:10.1158/1078-0432.CCR-1004-0018
Clinical Studies

Blood Pharmacokinetics of Various Monoclonal Antibodies Labeled with a New Trifunctional Chelating Reagent for Simultaneous Conjugation with 1,4,7,10-Tetraazacyclododecane-N,N′,N″,N‴-Tetraacetic Acid and Biotin before Radiolabeling

Zhongmin Wang, Linda Mårtensson, Rune Nilsson, Pär-Ola Bendahl, Lars Lindgren, Tomas Ohlsson, Hans-Olov Sjögren, Sven-Erik Strand and Jan Tennvall

Clin Cancer Res October 1 2005 11 (19) 7171s-7177s; DOI:10.1158/1078-0432.CCR-1004-0001
Clinical Studies

Radioimmunotherapy with [¹³¹I]cG250 in Patients with Metastasized Renal Cell Cancer: Dosimetric Analysis and Immunologic Response

Adrienne H. Brouwers, Wilhelmina C.A.M. Buijs, Peter F.A. Mulders, Pieter H.M. de Mulder, Wim J.M. van den Broek, Carola Mala, Egbert Oosterwijk, Otto C. Boerman, Frans H.M. Corstens and Wim J.G. Oyen

Clin Cancer Res October 1 2005 11 (19) 7178s-7186s; DOI:10.1158/1078-0432.CCR-1004-0010
Clinical Studies

Enhancement of the Therapeutic Index: From Nonmyeloablative and Myeloablative toward Pretargeted Radioimmunotherapy for Metastatic Prostate Cancer

Sally J. DeNardo, Carol M. Richman, Huguette Albrecht, Patricia A. Burke, Arut Natarajan, Aina Yuan, Jeff P. Gregg, R.T. O'Donnell and Gerald L. DeNardo

Clin Cancer Res October 1 2005 11 (19) 7187s-7194s; DOI:10.1158/1078-0432.CCR-1004-0013
Clinical Studies

Radioimmunotherapy of Prostate Cancer Using ⁹⁰Y- and ¹⁷⁷Lu-Labeled J591 Monoclonal Antibodies: Effect of Multiple Treatments on Myelotoxicity

Shankar Vallabhajosula, Stanley J. Goldsmith, Lale Kostakoglu, Mathew I. Milowsky, David M. Nanus and Neil H. Bander

Clin Cancer Res October 1 2005 11 (19) 7195s-7200s; DOI:10.1158/1078-0432.CCR-1004-0023
Clinical Studies

Concluding Remarks: Tenth Conference on Cancer Therapy with Antibodies and Immunoconjugates

Sally J. DeNardo

Clin Cancer Res October 1 2005 11 (19) 7201s-7202s; DOI:10.1158/1078-0432.CCR-1004-0024

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Editorials

The Biology Behind

Report from the FDA

Human Cancer Biology

Imaging, Diagnosis, Prognosis

Cancer Therapy: Clinical

Cancer Therapy: Preclinical

Cancer Prevention

Letters to the Editor

Introduction

Experimental Studies

Pretargeting Studies

Clinical Studies

Issue Highlights

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About Clinical Cancer Research