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Cancer Therapy: Preclinical

Irinotecan Inactivation Is Modulated by Epigenetic Silencing of UGT1A1 in Colon Cancer

Jean-François Gagnon, Olivier Bernard, Lyne Villeneuve, Bernard Têtu and Chantal Guillemette
Jean-François Gagnon
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Olivier Bernard
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Lyne Villeneuve
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Bernard Têtu
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Chantal Guillemette
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DOI: 10.1158/1078-0432.CCR-05-2130 Published March 2006
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Article Information

Volume 12, Issue 6, pp. 1850-1858

DOI 
https://doi.org/10.1158/1078-0432.CCR-05-2130
PubMed 
16551870

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Accepted January 9, 2006
  • Received September 29, 2005
  • Revision received December 5, 2005
  • Published first March 21, 2006.

Copyright & Usage 
American Association for Cancer Research

Author Information

  1. Jean-François Gagnon2,
  2. Olivier Bernard2,
  3. Lyne Villeneuve2,
  4. Bernard Têtu3 and
  5. Chantal Guillemette1,2
  1. Authors' Affiliations:1Canada Research Chair in Pharmacogenomics and 2Oncology and Molecular Endocrinology Research Center, Centre Hospitalier de l'Université Laval Research Center, Faculty of Pharmacy and 3Department of Pathology, Hôtel-Dieu de Québec, Laval University, Quebec, Canada
  1. Requests for reprints:
    Chantal Guillemette, Canada Research Chair in Pharmacogenomics, Pharmacogenomics Laboratory, Centre de Recherche du Centre Hospitalier de l'Université Laval Research Center, T3-67, 2705 Boul. Laurier, T3-48 Quebec, Canada G1V 4G2. Phone: 418-654-2296; Fax: 418-654-2761; E-mail: chantal.guillemette{at}crchul.ulaval.ca.
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Clinical Cancer Research: 12 (6)
March 2006
Volume 12, Issue 6
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Irinotecan Inactivation Is Modulated by Epigenetic Silencing of UGT1A1 in Colon Cancer
Jean-François Gagnon, Olivier Bernard, Lyne Villeneuve, Bernard Têtu and Chantal Guillemette
Clin Cancer Res March 15 2006 (12) (6) 1850-1858; DOI: 10.1158/1078-0432.CCR-05-2130

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Irinotecan Inactivation Is Modulated by Epigenetic Silencing of UGT1A1 in Colon Cancer
Jean-François Gagnon, Olivier Bernard, Lyne Villeneuve, Bernard Têtu and Chantal Guillemette
Clin Cancer Res March 15 2006 (12) (6) 1850-1858; DOI: 10.1158/1078-0432.CCR-05-2130
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Clinical Cancer Research
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