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Clinical Cancer Research
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Cancer Therapy: Clinical

Phase I and Pharmacokinetic Study of Vorinostat, A Histone Deacetylase Inhibitor, in Combination with Carboplatin and Paclitaxel for Advanced Solid Malignancies

Suresh S. Ramalingam, Robert A. Parise, Ramesh K. Ramananthan, Theodore F. Lagattuta, Lori A. Musguire, Ronald G. Stoller, Douglas M. Potter, Athanassios E. Argiris, James A. Zwiebel, Merrill J. Egorin and Chandra P. Belani
Suresh S. Ramalingam
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Robert A. Parise
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Ramesh K. Ramananthan
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Theodore F. Lagattuta
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Lori A. Musguire
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Ronald G. Stoller
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Douglas M. Potter
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Athanassios E. Argiris
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James A. Zwiebel
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Merrill J. Egorin
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Chandra P. Belani
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DOI: 10.1158/1078-0432.CCR-07-0162 Published June 2007
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Article Information

Volume 13, Issue 12, pp. 3605-3610

DOI 
https://doi.org/10.1158/1078-0432.CCR-07-0162
PubMed 
17510206

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Received January 19, 2007
  • Revision received February 28, 2007
  • Accepted March 7, 2007
  • Published first May 17, 2007.

Copyright & Usage 
American Association for Cancer Research

Author Information

  1. Suresh S. Ramalingam1,3,
  2. Robert A. Parise3,
  3. Ramesh K. Ramananthan1,3,
  4. Theodore F. Lagattuta3,
  5. Lori A. Musguire1,
  6. Ronald G. Stoller1,
  7. Douglas M. Potter4,5,
  8. Athanassios E. Argiris1,3,
  9. James A. Zwiebel6,
  10. Merrill J. Egorin1,2,3, and
  11. Chandra P. Belani1,3
  1. Authors' Affiliations:1Division of Hematology-Oncology, Department of Medicine and 2Deparment of Pharmacology, University of Pittsburgh School of Medicine; 3Molecular Therapeutics/Drug Discovery Program and 4Biostatistics Facility, University of Pittsburgh Cancer Institute; 5Biostatistics Department, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania and 6Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, Maryland
  1. Requests for reprints:
    Suresh S. Ramalingam, Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh School of Medicine, MD5150 Centre Avenue, Suite 555, UPMC Cancer Pavilion, Pittsburgh, PA 15232. Phone: 412-648-6619; Fax: 412-648-6579; E-mail: ramalingams{at}upmc.edu.
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Clinical Cancer Research: 13 (12)
June 2007
Volume 13, Issue 12
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Phase I and Pharmacokinetic Study of Vorinostat, A Histone Deacetylase Inhibitor, in Combination with Carboplatin and Paclitaxel for Advanced Solid Malignancies
Suresh S. Ramalingam, Robert A. Parise, Ramesh K. Ramananthan, Theodore F. Lagattuta, Lori A. Musguire, Ronald G. Stoller, Douglas M. Potter, Athanassios E. Argiris, James A. Zwiebel, Merrill J. Egorin and Chandra P. Belani
Clin Cancer Res June 15 2007 (13) (12) 3605-3610; DOI: 10.1158/1078-0432.CCR-07-0162

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Phase I and Pharmacokinetic Study of Vorinostat, A Histone Deacetylase Inhibitor, in Combination with Carboplatin and Paclitaxel for Advanced Solid Malignancies
Suresh S. Ramalingam, Robert A. Parise, Ramesh K. Ramananthan, Theodore F. Lagattuta, Lori A. Musguire, Ronald G. Stoller, Douglas M. Potter, Athanassios E. Argiris, James A. Zwiebel, Merrill J. Egorin and Chandra P. Belani
Clin Cancer Res June 15 2007 (13) (12) 3605-3610; DOI: 10.1158/1078-0432.CCR-07-0162
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