Differential Metabolism of Gefitinib and Erlotinib by Human Cytochrome P450 Enzymes

Jing Li; Ming Zhao; Ping He; Manuel Hidalgo; Sharyn D. Baker

doi:10.1158/1078-0432.CCR-07-0088

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Cancer Therapy: Preclinical

Differential Metabolism of Gefitinib and Erlotinib by Human Cytochrome P450 Enzymes

Jing Li, Ming Zhao, Ping He, Manuel Hidalgo and Sharyn D. Baker

Jing Li

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Ming Zhao

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Ping He

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Manuel Hidalgo

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Sharyn D. Baker

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DOI: 10.1158/1078-0432.CCR-07-0088 Published June 2007

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Article Information

Volume 13, Issue 12, pp. 3731-3737

DOI

https://doi.org/10.1158/1078-0432.CCR-07-0088

PubMed

17575239

Published By

American Association for Cancer Research

Print ISSN

1078-0432

Online ISSN

1557-3265

History

Received January 15, 2007
Revision received March 7, 2007
Accepted March 22, 2007
Published first June 15, 2007.

American Association for Cancer Research

Author Information

Jing Li,
Ming Zhao,
Ping He,
Manuel Hidalgo, and
Sharyn D. Baker

Authors' Affiliation: The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland

Requests for reprints:
Sharyn D. Baker, Pharmaceutical Sciences Department, St. Jude Children's Research Hospital, 332 North Lauderdale Street, DTRC Room D1034, Mail Stop 314, Memphis, TN 38105. Phone: 901-495-3089; Fax: 901-495-3125; E-mail: sharyn.baker{at}stjude.org.

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June 2007
Volume 13, Issue 12

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Differential Metabolism of Gefitinib and Erlotinib by Human Cytochrome P450 Enzymes