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Cancer Therapy: Clinical

Phase I Evaluation of a Fully Human Anti–αv Integrin Monoclonal Antibody (CNTO 95) in Patients with Advanced Solid Tumors

Saifee A. Mullamitha, Nhuan C. Ton, Geoff J.M. Parker, Alan Jackson, Peter J. Julyan, Caleb Roberts, Gio A. Buonaccorsi, Yvonne Watson, Karen Davies, Sue Cheung, Lynn Hope, Juan W. Valle, John A. Radford, Jeremy Lawrance, Mark P. Saunders, Mihaela C. Munteanu, Marian T. Nakada, Jeffrey A. Nemeth, Hugh M. Davis, Qun Jiao, Uma Prabhakar, Zhihui Lang, Robert E. Corringham, Robert A. Beckman and Gordon C. Jayson
Saifee A. Mullamitha
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Nhuan C. Ton
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Geoff J.M. Parker
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DOI: 10.1158/1078-0432.CCR-06-2779 Published April 2007
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ARTICLE USAGE: April 2007 to January 2021

AbstractFull-text HTMLPDF
Total286933832372

Cited By

Article Information

Volume 13, Issue 7, pp. 2128-2135

DOI 
https://doi.org/10.1158/1078-0432.CCR-06-2779
PubMed 
17404096

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Accepted January 25, 2007
  • Received November 27, 2006
  • Revision received January 15, 2007
  • Published first April 2, 2007.

Copyright & Usage 
American Association for Cancer Research

Author Information

  1. Saifee A. Mullamitha1,
  2. Nhuan C. Ton1,
  3. Geoff J.M. Parker3,
  4. Alan Jackson3,
  5. Peter J. Julyan2,
  6. Caleb Roberts3,
  7. Gio A. Buonaccorsi3,
  8. Yvonne Watson3,
  9. Karen Davies3,
  10. Sue Cheung3,
  11. Lynn Hope1,
  12. Juan W. Valle1,
  13. John A. Radford1,
  14. Jeremy Lawrance1,
  15. Mark P. Saunders1,
  16. Mihaela C. Munteanu4,
  17. Marian T. Nakada5,
  18. Jeffrey A. Nemeth5,
  19. Hugh M. Davis6,
  20. Qun Jiao6,
  21. Uma Prabhakar6,
  22. Zhihui Lang7,
  23. Robert E. Corringham7,
  24. Robert A. Beckman7,
  25. Gordon C. Jayson1 and
  26. in association with the Biotherapy Development Association
  1. Authors' Affiliations:1Cancer Research UK and 2Department of Medical Physics, Christie Hospital, Withington; 3Imaging Science and Biomedical Engineering, University of Manchester, Manchester, United Kingdom; and 4Department of Clinical Trial Management, 5Oncology Discovery Research, 6Clinical Pharmacology, and 7Oncology Clinical Research and Development, Centocor Research and Development, Inc., Malvern, Pennsylvania
  1. Requests for reprints:
    Gordon Jayson, Department of Medical Oncology, Christie Hospital, Wilmslow Road, Withington, Manchester M20 4BX, United Kingdom. Phone: 44-161-446-3606; Fax: 44-161-446-8565; E-mail: Gordon.Jayson{at}christie-tr.nwest.nhs.uk.
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Clinical Cancer Research: 13 (7)
April 2007
Volume 13, Issue 7
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Phase I Evaluation of a Fully Human Anti–αv Integrin Monoclonal Antibody (CNTO 95) in Patients with Advanced Solid Tumors
Saifee A. Mullamitha, Nhuan C. Ton, Geoff J.M. Parker, Alan Jackson, Peter J. Julyan, Caleb Roberts, Gio A. Buonaccorsi, Yvonne Watson, Karen Davies, Sue Cheung, Lynn Hope, Juan W. Valle, John A. Radford, Jeremy Lawrance, Mark P. Saunders, Mihaela C. Munteanu, Marian T. Nakada, Jeffrey A. Nemeth, Hugh M. Davis, Qun Jiao, Uma Prabhakar, Zhihui Lang, Robert E. Corringham, Robert A. Beckman and Gordon C. Jayson
Clin Cancer Res April 1 2007 (13) (7) 2128-2135; DOI: 10.1158/1078-0432.CCR-06-2779

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Phase I Evaluation of a Fully Human Anti–αv Integrin Monoclonal Antibody (CNTO 95) in Patients with Advanced Solid Tumors
Saifee A. Mullamitha, Nhuan C. Ton, Geoff J.M. Parker, Alan Jackson, Peter J. Julyan, Caleb Roberts, Gio A. Buonaccorsi, Yvonne Watson, Karen Davies, Sue Cheung, Lynn Hope, Juan W. Valle, John A. Radford, Jeremy Lawrance, Mark P. Saunders, Mihaela C. Munteanu, Marian T. Nakada, Jeffrey A. Nemeth, Hugh M. Davis, Qun Jiao, Uma Prabhakar, Zhihui Lang, Robert E. Corringham, Robert A. Beckman and Gordon C. Jayson
Clin Cancer Res April 1 2007 (13) (7) 2128-2135; DOI: 10.1158/1078-0432.CCR-06-2779
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