Table of Contents

Cancer Therapy: Preclinical

• Cancer Therapy: Preclinical

  Sulforaphane Enhances the Therapeutic Potential of TRAIL in Prostate Cancer Orthotopic Model through Regulation of Apoptosis, Metastasis, and Angiogenesis

  Sharmila Shankar, Suthakar Ganapathy and Rakesh K. Srivastava

  Clin Cancer Res November 1 2008 14 (21) 6855-6866; DOI:10.1158/1078-0432.CCR-08-0903

  
  
• Cancer Therapy: Preclinical

  Reduced Erlotinib Sensitivity of Epidermal Growth Factor Receptor-Mutant Non–Small Cell Lung Cancer following Cisplatin Exposure: A Cell Culture Model of Second-line Erlotinib Treatment

  Tan Min Chin, Margaret P. Quinlan, Anurag Singh, Lecia V. Sequist, Thomas J. Lynch, Daniel A. Haber, Sreenath V. Sharma and Jeffrey Settleman

  Clin Cancer Res November 1 2008 14 (21) 6867-6876; DOI:10.1158/1078-0432.CCR-08-0093

  
  
• Cancer Therapy: Preclinical

  Preclinical Modeling of a Phase 0 Clinical Trial: Qualification of a Pharmacodynamic Assay of Poly (ADP-Ribose) Polymerase in Tumor Biopsies of Mouse Xenografts

  Robert J. Kinders, Melinda Hollingshead, Sonny Khin, Larry Rubinstein, Joseph E. Tomaszewski, James H. Doroshow, Ralph E. Parchment and the National Cancer Institute Phase 0 Clinical Trials Team

  Clin Cancer Res November 1 2008 14 (21) 6877-6885; DOI:10.1158/1078-0432.CCR-08-0214

  
  
• Cancer Therapy: Preclinical

  A Multiple-Loop, Double-Cube Microarray Design Applied to Prostate Cancer Cell Lines with Variable Sensitivity to Histone Deacetylase Inhibitors

  Madeleine S.Q. Kortenhorst, Marianna Zahurak, Shabana Shabbeer, Sushant Kachhap, Nathan Galloway, Giovanni Parmigiani, Henk M.W. Verheul and Michael A. Carducci

  Clin Cancer Res November 1 2008 14 (21) 6886-6894; DOI:10.1158/1078-0432.CCR-08-0119

  
  
• Cancer Therapy: Preclinical

  Therapeutic Antitumor Efficacy of Anti-CD137 Agonistic Monoclonal Antibody in Mouse Models of Myeloma

  Oihana Murillo, Ainhoa Arina, Sandra Hervas-Stubbs, Anjana Gupta, Brandon McCluskey, Juan Dubrot, Asís Palazón, Arantza Azpilikueta, Maria C. Ochoa, Carlos Alfaro, Sarai Solano, José L. Pérez-Gracia, Babatunde O. Oyajobi and Ignacio Melero

  Clin Cancer Res November 1 2008 14 (21) 6895-6906; DOI:10.1158/1078-0432.CCR-08-0285

  
  
• Cancer Therapy: Preclinical

  Bendamustine Is Effective in p53-Deficient B-Cell Neoplasms and Requires Oxidative Stress and Caspase-Independent Signaling

  Gaël Roué, Mónica López-Guerra, Pierre Milpied, Patricia Pérez-Galán, Neus Villamor, Emili Montserrat, Elias Campo and Dolors Colomer

  Clin Cancer Res November 1 2008 14 (21) 6907-6915; DOI:10.1158/1078-0432.CCR-08-0388

  
  
• Cancer Therapy: Preclinical

  Identification of an Immunogenic CTL Epitope of HIFPH3 for Immunotherapy of Renal Cell Carcinoma

  Eiji Sato, Toshihiko Torigoe, Yoshihiko Hirohashi, Hiroshi Kitamura, Toshiaki Tanaka, Ichiya Honma, Hiroko Asanuma, Kenji Harada, Hideo Takasu, Naoya Masumori, Naoki Ito, Tadashi Hasegawa, Taiji Tsukamoto and Noriyuki Sato

  Clin Cancer Res November 1 2008 14 (21) 6916-6923; DOI:10.1158/1078-0432.CCR-08-0466

  
  
• Cancer Therapy: Preclinical

  Ankyrin Repeat Domain 1, ANKRD1, a Novel Determinant of Cisplatin Sensitivity Expressed in Ovarian Cancer

  Lyndee L. Scurr, Alexander D. Guminski, Yoke-Eng Chiew, Rosemary L. Balleine, Raghwa Sharma, Ying Lei, Kylie Pryor, Gerard V. Wain, Alison Brand, Karen Byth, Catherine Kennedy, Helen Rizos, Paul R. Harnett and Anna deFazio

  Clin Cancer Res November 1 2008 14 (21) 6924-6932; DOI:10.1158/1078-0432.CCR-07-5189

  
  
• Cancer Therapy: Preclinical

  DNA Vaccines Targeting Tumor Antigens to B7 Molecules on Antigen-Presenting Cells Induce Protective Antitumor Immunity and Delay Onset of HER-2/Neu-Driven Mammary Carcinoma

  Arjen Sloots, Cristina Mastini, Florian Rohrbach, Robert Weth, Claudia Curcio, Ute Burkhardt, Elke Jäger, Guido Forni, Federica Cavallo and Winfried S. Wels

  Clin Cancer Res November 1 2008 14 (21) 6933-6943; DOI:10.1158/1078-0432.CCR-08-1257

  
  
• Cancer Therapy: Preclinical

  Insulin-Like Growth Factor Binding Protein-2 Is a Novel Therapeutic Target Associated with Breast Cancer

  Alan I. So, Randy J. Levitt, Bernhard Eigl, Ladan Fazli, Motosugu Muramaki, Sam Leung, Maggie C.U. Cheang, Torsten O. Nielsen, Martin Gleave and Michael Pollak

  Clin Cancer Res November 1 2008 14 (21) 6944-6954; DOI:10.1158/1078-0432.CCR-08-0408

  
  
• Cancer Therapy: Preclinical

  Generation of Antitumor Invariant Natural Killer T Cell Lines in Multiple Myeloma and Promotion of Their Functions via Lenalidomide: A Strategy for Immunotherapy

  Weihua Song, Hans J.J. van der Vliet, Yu-Tzu Tai, Rao Prabhala, Ruojie Wang, Klaus Podar, Laurence Catley, Masood A. Shammas, Kenneth C. Anderson, Steven P. Balk, Mark A. Exley and Nikhil C. Munshi

  Clin Cancer Res November 1 2008 14 (21) 6955-6962; DOI:10.1158/1078-0432.CCR-07-5290

  
  
• Cancer Therapy: Preclinical

  Autocrine Production of Amphiregulin Predicts Sensitivity to Both Gefitinib and Cetuximab in EGFR Wild-type Cancers

  Kimio Yonesaka, Kreshnik Zejnullahu, Neal Lindeman, Alison J. Homes, David M. Jackman, Feng Zhao, Andrew M. Rogers, Bruce E. Johnson and Pasi A. Jänne

  Clin Cancer Res November 1 2008 14 (21) 6963-6973; DOI:10.1158/1078-0432.CCR-08-0957