Abstract
Monoclonal gammopathy of undetermined significance (MGUS) is a common premalignant plasma cell proliferative disorder with a lifelong risk of progression to multiple myeloma. Because myeloma is an incurable malignancy, strategies to delay or prevent progression in high-risk patients are of considerable importance. (Clin Cancer Res 2009;15(18):5606–8)
Footnotes
Grant support: Supported in part by grants CA62242 and CA107476 from the National Cancer Institute, Bethesda, MD.
- Received July 7, 2009.
- Accepted July 13, 2009.
September 2009
Volume 15, Issue 18
Volume 15, Issue 18
Prevention of Progression in Monoclonal Gammopathy of Undetermined Significance
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- Article
- Abstract
- Etiologic Factors for MGUS and Prospects for Primary Prevention
- Implications of Discrete Cytogenetically Defined Subtypes of MGUS
- Progression of MGUS to Myeloma and Secondary Prevention
- Clinical Implications
- Future Chemoprevention Trials in MGUS and SMM
- Disclosure of Potential Conflicts of Interest
- Note in Proof
- Footnotes
- References
- Figures & Data
- Info & Metrics
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