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Cancer Therapy: Preclinical

Silibinin Suppresses Growth of Human Prostate Carcinoma PC-3 Orthotopic Xenograft via Activation of Extracellular Signal-Regulated Kinase 1/2 and Inhibition of Signal Transducers and Activators of Transcription Signaling

Rana P. Singh, Komal Raina, Gagan Deep, Daniel Chan and Rajesh Agarwal
Rana P. Singh
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Komal Raina
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Gagan Deep
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Daniel Chan
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Rajesh Agarwal
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DOI: 10.1158/1078-0432.CCR-08-1846 Published January 2009
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Article Information

Volume 15, Issue 2, pp. 613-621

DOI 
https://doi.org/10.1158/1078-0432.CCR-08-1846
PubMed 
19147767

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Accepted September 23, 2008
  • Received July 16, 2008
  • Revision received September 16, 2008
  • Published first January 15, 2009.

Copyright & Usage 
American Association for Cancer Research

Author Information

  1. Rana P. Singh1,4,
  2. Komal Raina1,
  3. Gagan Deep1,
  4. Daniel Chan2,3 and
  5. Rajesh Agarwal1,3
  1. Authors' Affiliations:1Department of Pharmaceutical Sciences, School of Pharmacy, 2Division of Medical Oncology, School of Medicine, and 3University of Colorado Cancer Center, University of Colorado-Denver, Denver, Colorado and 4Cancer Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India
  1. Requests for reprints:
    Rajesh Agarwal, Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado-Denver, 4200 East Ninth Street, Box C238, Denver, CO 80262. Phone: 303-315-1381; Fax: 303-315-6281; E-mail: Rajesh.Agarwal{at}uchsc.edu.
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Clinical Cancer Research: 15 (2)
January 2009
Volume 15, Issue 2
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Silibinin Suppresses Growth of Human Prostate Carcinoma PC-3 Orthotopic Xenograft via Activation of Extracellular Signal-Regulated Kinase 1/2 and Inhibition of Signal Transducers and Activators of Transcription Signaling
Rana P. Singh, Komal Raina, Gagan Deep, Daniel Chan and Rajesh Agarwal
Clin Cancer Res January 15 2009 (15) (2) 613-621; DOI: 10.1158/1078-0432.CCR-08-1846

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Silibinin Suppresses Growth of Human Prostate Carcinoma PC-3 Orthotopic Xenograft via Activation of Extracellular Signal-Regulated Kinase 1/2 and Inhibition of Signal Transducers and Activators of Transcription Signaling
Rana P. Singh, Komal Raina, Gagan Deep, Daniel Chan and Rajesh Agarwal
Clin Cancer Res January 15 2009 (15) (2) 613-621; DOI: 10.1158/1078-0432.CCR-08-1846
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