Table of Contents

Cancer Therapy: Preclinical

• Cancer Therapy: Preclinical

  Grape Seed Proanthocyanidins Inhibit the Growth of Human Non-Small Cell Lung Cancer Xenografts by Targeting Insulin-Like Growth Factor Binding Protein-3, Tumor Cell Proliferation, and Angiogenic Factors

  Suhail Akhtar, Syed M. Meeran, Nandan Katiyar and Santosh K. Katiyar

  Clin Cancer Res February 1 2009 15 (3) 821-831; DOI:10.1158/1078-0432.CCR-08-1901

  
  
• Cancer Therapy: Preclinical

  CAT-8015: A Second-Generation Pseudomonas Exotoxin A–Based Immunotherapy Targeting CD22-Expressing Hematologic Malignancies

  Ralph F. Alderson, Robert J. Kreitman, Tianling Chen, Peter Yeung, Ronald Herbst, Judy A. Fox and Ira Pastan

  Clin Cancer Res February 1 2009 15 (3) 832-839; DOI:10.1158/1078-0432.CCR-08-1456

  
  
• Cancer Therapy: Preclinical

  Dual Degradation of Aurora A and B Kinases by the Histone Deacetylase Inhibitor LBH589 Induces G₂-M Arrest and Apoptosis of Renal Cancer Cells

  Tai-Lung Cha, Mei-Jen Chuang, Sheng-Tang Wu, Guang-Huan Sun, Sun-Yran Chang, Dah-Shyong Yu, Shih-Ming Huang, Steven Kuan-Hua Huan, Tse-Chou Cheng, Tzu-Ting Chen, Pao-Luo Fan and Pei-Wen Hsiao

  Clin Cancer Res February 1 2009 15 (3) 840-850; DOI:10.1158/1078-0432.CCR-08-1918

  
  
• Cancer Therapy: Preclinical

  In vivo Model of Follicular Lymphoma Resistant to Rituximab

  Stéphane Dalle, Sophie Dupire, Stéphanie Brunet-Manquat, Lina Reslan, Adriana Plesa and Charles Dumontet

  Clin Cancer Res February 1 2009 15 (3) 851-857; DOI:10.1158/1078-0432.CCR-08-1685

  
  
• Cancer Therapy: Preclinical

  Antitumor Alkyl Ether Lipid Edelfosine: Tissue Distribution and Pharmacokinetic Behavior in Healthy and Tumor-Bearing Immunosuppressed Mice

  Ander Estella-Hermoso de Mendoza, Miguel A. Campanero, Janis de la Iglesia-Vicente, Consuelo Gajate, Faustino Mollinedo and María J. Blanco-Prieto

  Clin Cancer Res February 1 2009 15 (3) 858-864; DOI:10.1158/1078-0432.CCR-08-1654

  
  
• Cancer Therapy: Preclinical

  Inhibition of Micrometastatic Prostate Cancer Cell Spread in Animal Models By ²¹³Bilabeled Multiple Targeted α Radioimmunoconjugates

  Yong Li, Emma Song, Syed M. Abbas Rizvi, Carl A. Power, Julia Beretov, Chand Raja, Paul J. Cozzi, Alfred Morgenstern, Christos Apostolidis, Barry J. Allen and Pamela J. Russell

  Clin Cancer Res February 1 2009 15 (3) 865-875; DOI:10.1158/1078-0432.CCR-08-1203

  
  
• Cancer Therapy: Preclinical

  Targeted Photothermal Ablation of Murine Melanomas with Melanocyte-Stimulating Hormone Analog–Conjugated Hollow Gold Nanospheres

  Wei Lu, Chiyi Xiong, Guodong Zhang, Qian Huang, Rui Zhang, Jin Z. Zhang and Chun Li

  Clin Cancer Res February 1 2009 15 (3) 876-886; DOI:10.1158/1078-0432.CCR-08-1480

  
  
• Cancer Therapy: Preclinical

  Potential Therapeutic Effect of Glycogen Synthase Kinase 3β Inhibition against Human Glioblastoma

  Katsuyoshi Miyashita, Kazuyuki Kawakami, Mitsutoshi Nakada, Wei Mai, Abbas Shakoori, Hironori Fujisawa, Yutaka Hayashi, Jun-ichiro Hamada and Toshinari Minamoto

  Clin Cancer Res February 1 2009 15 (3) 887-897; DOI:10.1158/1078-0432.CCR-08-0760

  
  
• Cancer Therapy: Preclinical

  In vitro and In vivo Anticancer Effects of the Novel Vitamin E Ether Analogue RRR-α-Tocopheryloxybutyl Sulfonic Acid in Prostate Cancer

  Jing Ni, Tiejun Mai, See-Tong Pang, Imranul Haque, Kaohsing Huang, Matthew A. DiMaggio, Shaozhen Xie, Nadine S. James, Dhanalakshmi Kasi, Sherry R. Chemler and Shuyuan Yeh

  Clin Cancer Res February 1 2009 15 (3) 898-906; DOI:10.1158/1078-0432.CCR-08-1087

  
  
• Cancer Therapy: Preclinical

  Addition of S-1 to the Epidermal Growth Factor Receptor Inhibitor Gefitinib Overcomes Gefitinib Resistance in Non–small cell Lung Cancer Cell Lines with MET Amplification

  Takafumi Okabe, Isamu Okamoto, Sayaka Tsukioka, Junji Uchida, Erina Hatashita, Yuki Yamada, Takeshi Yoshida, Kazuto Nishio, Masahiro Fukuoka, Pasi A. Jänne and Kazuhiko Nakagawa

  Clin Cancer Res February 1 2009 15 (3) 907-913; DOI:10.1158/1078-0432.CCR-08-2251

  
  
• Cancer Therapy: Preclinical

  Ionizing Radiation Up-regulates Telomerase Activity in Cancer Cell Lines by Post-translational Mechanism via Ras/Phosphatidylinositol 3-Kinase/Akt Pathway

  Ron Ram, Orit Uziel, Orit Eldan, Eyal Fenig, Einat Beery, Shelly Lichtenberg, Yardena Nordenberg and Meir Lahav

  Clin Cancer Res February 1 2009 15 (3) 914-923; DOI:10.1158/1078-0432.CCR-08-0792

  
  
• Cancer Therapy: Preclinical

  A Novel Human Her-2/neu Chimeric Molecule Expressed by Listeria monocytogenes Can Elicit Potent HLA-A2 Restricted CD8-positive T cell Responses and Impact the Growth and Spread of Her-2/neu-positive Breast Tumors

  Matthew M. Seavey, Zhen-Kun Pan, Paulo C. Maciag, Anu Wallecha, Sandra Rivera, Yvonne Paterson and Vafa Shahabi

  Clin Cancer Res February 1 2009 15 (3) 924-932; DOI:10.1158/1078-0432.CCR-08-2283

  
  
• Cancer Therapy: Preclinical

  MDM2 Antagonist Nutlin-3 Displays Antiproliferative and Proapoptotic Activity in Mantle Cell Lymphoma

  Yoko Tabe, Denise Sebasigari, Linhua Jin, Martina Rudelius, Theresa Davies-Hill, Kazunori Miyake, Takashi Miida, Stefania Pittaluga and Mark Raffeld

  Clin Cancer Res February 1 2009 15 (3) 933-942; DOI:10.1158/1078-0432.CCR-08-0399

  
  
• Cancer Therapy: Preclinical

  Genetically Targeted T Cells Eradicate Established Breast Cancer in Syngeneic Mice

  Hao Wang, Huafeng Wei, Ruiping Zhang, Sheng Hou, Bohua Li, Weizhu Qian, Dapeng Zhang, Gen Kou, Jianxin Dai and Yajun Guo

  Clin Cancer Res February 1 2009 15 (3) 943-950; DOI:10.1158/1078-0432.CCR-08-2381

  
  
• Cancer Therapy: Preclinical

  Human-Like Mouse Models for Testing the Efficacy and Safety of Anti-β₂-Microglobulin Monoclonal Antibodies to Treat Myeloma

  Jing Yang, Yabing Cao, Sungyongl Hong, Haiyan Li, Jianfei Qian, Larry W. Kwak and Qing Yi

  Clin Cancer Res February 1 2009 15 (3) 951-959; DOI:10.1158/1078-0432.CCR-08-1823

  
  
• Cancer Therapy: Preclinical

  B7 Blockade Alters the Balance between Regulatory T Cells and Tumor-reactive T Cells for Immunotherapy of Cancer

  Penghui Zhou, Xincheng Zheng, Huiming Zhang, Yang Liu and Pan Zheng

  Clin Cancer Res February 1 2009 15 (3) 960-970; DOI:10.1158/1078-0432.CCR-08-1611