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Clinical Cancer Research
Clinical Cancer Research
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Table of Contents

Highlights

  • Highlights
    Highlights of This Issue
    Clin Cancer Res June 1 2010 16 (11) 2919-2919;

CCR New Strategies

  • CCR New Strategies
    New Strategies for Treatment of KRAS Mutant Metastatic Colorectal Cancer
    Hans Prenen, Sabine Tejpar and Eric Van Cutsem
    Clin Cancer Res June 1 2010 16 (11) 2921-2926; DOI:10.1158/1078-0432.CCR-09-2029

Molecular Pathways

  • Molecular Pathways
    CXCL12 (SDF-1)/CXCR4 Pathway in Cancer
    Beverly A. Teicher and Simon P. Fricker
    Clin Cancer Res June 1 2010 16 (11) 2927-2931; DOI:10.1158/1078-0432.CCR-09-2329

  • Molecular Pathways
    Control of Tumorigenesis and Chemoresistance by the DEK Oncogene
    Erica Riveiro-Falkenbach and María S. Soengas
    Clin Cancer Res June 1 2010 16 (11) 2932-2938; DOI:10.1158/1078-0432.CCR-09-2330

Human Cancer Biology

  • Human Cancer Biology
    The Proapoptotic Molecule BLID Interacts with Bcl-XL and Its Downregulation in Breast Cancer Correlates with Poor Disease-Free and Overall Survival
    Constantinos G. Broustas, Jeffrey S. Ross, Qifeng Yang, Christine E. Sheehan, Rebecca Riggins, Anne-Michelle Noone, Bassem R. Haddad, Françoise Seillier-Moiseiwitsch, Bhaskar V.S. Kallakury, Bruce G. Haffty, Robert Clarke and Usha N. Kasid
    Clin Cancer Res June 1 2010 16 (11) 2939-2948; DOI:10.1158/1078-0432.CCR-09-2351

  • Human Cancer Biology
    The Tumor Suppressor UCHL1 Forms a Complex with p53/MDM2/ARF to Promote p53 Signaling and Is Frequently Silenced in Nasopharyngeal Carcinoma
    Lili Li, Qian Tao, Hongchuan Jin, Andrew van Hasselt, Fan Fong Poon, Xian Wang, Mu-Sheng Zeng, Wei-Hua Jia, Yi-Xin Zeng, Anthony T.C. Chan and Ya Cao
    Clin Cancer Res June 1 2010 16 (11) 2949-2958; DOI:10.1158/1078-0432.CCR-09-3178

  • Human Cancer Biology
    The Transcriptional Coregulator RIP140 Represses E2F1 Activity and Discriminates Breast Cancer Subtypes
    Aurélie Docquier, Pierre-Olivier Harmand, Samuel Fritsch, Maïa Chanrion, Jean-Marie Darbon and Vincent Cavaillès
    Clin Cancer Res June 1 2010 16 (11) 2959-2970; DOI:10.1158/1078-0432.CCR-09-3153

  • Human Cancer Biology
    Chromosomal and MicroRNA Expression Patterns Reveal Biologically Distinct Subgroups of 11q− Neuroblastoma
    Patrick G. Buckley, Leah Alcock, Kenneth Bryan, Isabella Bray, Johannes H. Schulte, Alexander Schramm, Angelika Eggert, Pieter Mestdagh, Katleen De Preter, Jo Vandesompele, Frank Speleman and Raymond L. Stallings
    Clin Cancer Res June 1 2010 16 (11) 2971-2978; DOI:10.1158/1078-0432.CCR-09-3215

  • Human Cancer Biology
    Telomere Maintenance and DNA Damage Responses during Lung Carcinogenesis
    Sylvie Lantuejoul, Christophe Raynaud, Dimitri Salameire, Sylvie Gazzeri, Denis Moro-Sibilot, Jean-Charles Soria, Christian Brambilla and Elizabeth Brambilla
    Clin Cancer Res June 1 2010 16 (11) 2979-2988; DOI:10.1158/1078-0432.CCR-10-0142

Cancer Therapy: Preclinical

  • Cancer Therapy: Preclinical | Free Article
    Assessment of the In vivo Antitumor Effects of ENMD-2076, a Novel Multitargeted Kinase Inhibitor, against Primary and Cell Line–Derived Human Colorectal Cancer Xenograft Models
    John J. Tentler, Erica L. Bradshaw-Pierce, Natalie J. Serkova, Kendra M. Hasebroock, Todd M. Pitts, Jennifer R. Diamond, Graham C. Fletcher, Mark R. Bray and S. Gail Eckhardt
    Clin Cancer Res June 1 2010 16 (11) 2989-2998; DOI:10.1158/1078-0432.CCR-10-0325

  • Cancer Therapy: Preclinical
    Insulin-like Growth Factor 2 Expression Modulates Taxol Resistance and Is a Candidate Biomarker for Reduced Disease-Free Survival in Ovarian Cancer
    Gloria S. Huang, Jurriaan Brouwer-Visser, Marissa J. Ramirez, Christine H. Kim, Tiffany M. Hebert, Juan Lin, Hugo Arias-Pulido, Clifford R. Qualls, Eric R. Prossnitz, Gary L. Goldberg, Harriet O. Smith and Susan Band Horwitz
    Clin Cancer Res June 1 2010 16 (11) 2999-3010; DOI:10.1158/1078-0432.CCR-09-3233

Imaging, Diagnosis, Prognosis

  • Imaging, Diagnosis, Prognosis
    Fibroblast Growth Factor Receptor 3 Mutation Analysis on Voided Urine for Surveillance of Patients with Low-Grade Non-Muscle–Invasive Bladder Cancer
    Tahlita C.M. Zuiverloon, Madelon N.M. van der Aa, Theo H. van der Kwast, Ewout W. Steyerberg, Hester F. Lingsma, Chris H. Bangma and Ellen C. Zwarthoff
    Clin Cancer Res June 1 2010 16 (11) 3011-3018; DOI:10.1158/1078-0432.CCR-09-3013

Cancer Therapy: Clinical

  • Cancer Therapy: Clinical
    A Phase I Study of 5-Fluorouracil/Leucovorin and Arsenic Trioxide for Patients with Refractory/Relapsed Colorectal Carcinoma
    Bach Ardalan, Pochi R. Subbarayan, Yipsel Ramos, Michael Gonzalez, Anthony Fernandez, Dmitry Mezentsev, Isildinha Reis, Robert Duncan, Lisa Podolsky, Kelvin Lee, Mayra Lima and Parvin Ganjei-Azar
    Clin Cancer Res June 1 2010 16 (11) 3019-3027; DOI:10.1158/1078-0432.CCR-09-2590

  • Cancer Therapy: Clinical
    Clinical and Correlative Results of SWOG S0354: A Phase II Trial of CNTO328 (Siltuximab), a Monoclonal Antibody against Interleukin-6, in Chemotherapy-Pretreated Patients with Castration-Resistant Prostate Cancer
    Tanya B. Dorff, Bryan Goldman, Jacek K. Pinski, Philip C. Mack, Primo N. Lara Jr., Peter J. Van Veldhuizen Jr., David I. Quinn, Nicholas J. Vogelzang, Ian M. Thompson Jr. and Maha H.A. Hussain
    Clin Cancer Res June 1 2010 16 (11) 3028-3034; DOI:10.1158/1078-0432.CCR-09-3122

  • Cancer Therapy: Clinical
    Oncolytic Adenovirus ICOVIR-7 in Patients with Advanced and Refractory Solid Tumors
    Petri Nokisalmi, Sari Pesonen, Sophie Escutenaire, Merja Särkioja, Mari Raki, Vincenzo Cerullo, Leena Laasonen, Ramon Alemany, Juan Rojas, Manel Cascallo, Kilian Guse, Maria Rajecki, Lotta Kangasniemi, Elina Haavisto, Aila Karioja-Kallio, Päivi Hannuksela, Minna Oksanen, Anna Kanerva, Timo Joensuu, Laura Ahtiainen and Akseli Hemminki
    Clin Cancer Res June 1 2010 16 (11) 3035-3043; DOI:10.1158/1078-0432.CCR-09-3167

  • Cancer Therapy: Clinical
    Phase 1 Study of AMG 386, a Selective Angiopoietin 1/2–Neutralizing Peptibody, in Combination with Chemotherapy in Adults with Advanced Solid Tumors
    Alain C. Mita, Chris H. Takimoto, Monica Mita, Anthony Tolcher, Kamalesh Sankhala, John Sarantopoulos, Manuel Valdivieso, Leslie Wood, Erik Rasmussen, Yu-Nien Sun, Z. Don Zhong, Michael B. Bass, NgocDiep Le and Patricia LoRusso
    Clin Cancer Res June 1 2010 16 (11) 3044-3056; DOI:10.1158/1078-0432.CCR-09-3368

  • Cancer Therapy: Clinical
    A Pharmacodynamic Study of Rapamycin in Men with Intermediate- to High-Risk Localized Prostate Cancer
    Andrew J. Armstrong, George J. Netto, Michelle A. Rudek, Susan Halabi, David P. Wood, Patricia A. Creel, Kelly Mundy, S. Lindsay Davis, Ting Wang, Roula Albadine, Luciana Schultz, Alan W. Partin, Antonio Jimeno, Helen Fedor, Phillip G. Febbo, Daniel J. George, Robin Gurganus, Angelo M. De Marzo and Michael A. Carducci
    Clin Cancer Res June 1 2010 16 (11) 3057-3066; DOI:10.1158/1078-0432.CCR-10-0124

  • Cancer Therapy: Clinical
    Two-Stage Phase I Dose-Escalation Study of Intratumoral Reovirus Type 3 Dearing and Palliative Radiotherapy in Patients with Advanced Cancers
    Kevin J. Harrington, Eleni M. Karapanagiotou, Victoria Roulstone, Katie R. Twigger, Christine L. White, Laura Vidal, Debbie Beirne, Robin Prestwich, Kate Newbold, Merina Ahmed, Khin Thway, Christopher M. Nutting, Matt Coffey, Dean Harris, Richard G. Vile, Hardev S. Pandha, Johann S. DeBono and Alan A. Melcher
    Clin Cancer Res June 1 2010 16 (11) 3067-3077; DOI:10.1158/1078-0432.CCR-10-0054

  • Cancer Therapy: Clinical
    A Multicenter Phase II Study of Erlotinib and Sorafenib in Chemotherapy-Naïve Patients with Advanced Non–Small Cell Lung Cancer
    Joline S.W. Lind, Anne-Marie C. Dingemans, Harry J.M. Groen, Frederik B. Thunnissen, Otto Bekers, Daniëlle A.M. Heideman, Richard J. Honeywell, Elisa Giovannetti, Godefridus J. Peters, Pieter E. Postmus, Robert Jan van Suylen and Egbert F. Smit
    Clin Cancer Res June 1 2010 16 (11) 3078-3087; DOI:10.1158/1078-0432.CCR-09-3033

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Clinical Cancer Research: 16 (11)
June 2010
Volume 16, Issue 11
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Issue Highlights

  • New Strategies for Treatment of KRAS Mutant Metastatic Colorectal Cancer
  • CXCL12 (SDF-1)/CXCR4 Pathway in Cancer
  • Oncolytic Adenovirus ICOVIR-7 in Patients with Advanced and Refractory Solid Tumors
  • The Proapoptotic Molecule BLID Interacts with Bcl-XL and Its Downregulation in Breast Cancer Correlates with Poor Disease-Free and Overall Survival

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  • Toxicity Management Affects Checkpoint Inhibitor Efficacy
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Clinical Cancer Research
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