Clinical Cancer Research: 16 (12)

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Highlights of This Issue

Clin Cancer Res June 15 2010 16 (12) 3089-3089;

CCR Translations

CCR Translations

How to Train Your Biomarker

Douglas Yee

Clin Cancer Res June 15 2010 16 (12) 3091-3093; DOI:10.1158/1078-0432.CCR-10-0873

Molecular Pathways

Molecular Pathways

Inhibition of the PI3K Pathway: Hope We Can Believe in?

Michiel S. van der Heijden and René Bernards

Clin Cancer Res June 15 2010 16 (12) 3094-3099; DOI:10.1158/1078-0432.CCR-09-3004
Molecular Pathways

Immunogenic Tumor Cell Death for Optimal Anticancer Therapy: The Calreticulin Exposure Pathway

Laurence Zitvogel, Oliver Kepp, Laura Senovilla, Laurie Menger, Nathalie Chaput and Guido Kroemer

Clin Cancer Res June 15 2010 16 (12) 3100-3104; DOI:10.1158/1078-0432.CCR-09-2891

CCR Focus

CCR Focus

Drugs That Target the Stemness Pathways

Susan E. Bates

Clin Cancer Res June 15 2010 16 (12) 3105-3105; DOI:10.1158/1078-0432.CCR-10-1127
CCR Focus

Controversies in Cancer Stem Cells: Targeting Embryonic Signaling Pathways

Naoko Takebe and S. Percy Ivy

Clin Cancer Res June 15 2010 16 (12) 3106-3112; DOI:10.1158/1078-0432.CCR-09-2934
CCR Focus

Cancer Stem Cells and Self-renewal

Catherine Adell O'Brien, Antonija Kreso and Catriona H.M. Jamieson

Clin Cancer Res June 15 2010 16 (12) 3113-3120; DOI:10.1158/1078-0432.CCR-09-2824
CCR Focus

The Difficulty of Targeting Cancer Stem Cell Niches

Mark A. LaBarge

Clin Cancer Res June 15 2010 16 (12) 3121-3129; DOI:10.1158/1078-0432.CCR-09-2933
CCR Focus

Targeting Hedgehog — a Cancer Stem Cell Pathway

Akil A. Merchant and William Matsui

Clin Cancer Res June 15 2010 16 (12) 3130-3140; DOI:10.1158/1078-0432.CCR-09-2846
CCR Focus

Targeting Notch to Target Cancer Stem Cells

Antonio Pannuti, Kimberly Foreman, Paola Rizzo, Clodia Osipo, Todd Golde, Barbara Osborne and Lucio Miele

Clin Cancer Res June 15 2010 16 (12) 3141-3152; DOI:10.1158/1078-0432.CCR-09-2823
CCR Focus

Targeting Wnt Signaling: Can We Safely Eradicate Cancer Stem Cells?

Fumi Takahashi-Yanaga and Michael Kahn

Clin Cancer Res June 15 2010 16 (12) 3153-3162; DOI:10.1158/1078-0432.CCR-09-2943

Human Cancer Biology

Human Cancer Biology

Molecular Diagnosis of Activating EGFR Mutations in Non–Small Cell Lung Cancer Using Mutation-Specific Antibodies for Immunohistochemical Analysis

Akihiko Kawahara, Chizuko Yamamoto, Kazutaka Nakashima, Koichi Azuma, Satoshi Hattori, Masaki Kashihara, Hisamichi Aizawa, Yuji Basaki, Michihiko Kuwano, Masayoshi Kage, Tetsuya Mitsudomi and Mayumi Ono

Clin Cancer Res June 15 2010 16 (12) 3163-3170; DOI:10.1158/1078-0432.CCR-09-3239
Human Cancer Biology

Aurora Kinase A Promotes Ovarian Tumorigenesis through Dysregulation of the Cell Cycle and Suppression of BRCA2

Gong Yang, Bin Chang, Fan Yang, Xiaoqing Guo, Kathy Qi Cai, Xue (Sherry) Xiao, Huamin Wang, Subrata Sen, Mien-Chie Hung, Gordon B. Mills, Sandy Chang, Asha S. Multani, Imelda Mercado-Uribe and Jinsong Liu

Clin Cancer Res June 15 2010 16 (12) 3171-3181; DOI:10.1158/1078-0432.CCR-09-3171

Cancer Therapy: Preclinical

Cancer Therapy: Preclinical

FTY720 Shows Promising In vitro and In vivo Preclinical Activity by Downmodulating Cyclin D1 and Phospho-Akt in Mantle Cell Lymphoma

Qing Liu, Lapo Alinari, Ching-Shih Chen, Fengting Yan, James T. Dalton, Rosa Lapalombella, Xiaoli Zhang, Rajeswaran Mani, Teresa Lin, John C. Byrd, Robert A. Baiocchi and Natarajan Muthusamy

Clin Cancer Res June 15 2010 16 (12) 3182-3192; DOI:10.1158/1078-0432.CCR-09-2484
Cancer Therapy: Preclinical

Development of an Integrated Genomic Classifier for a Novel Agent in Colorectal Cancer: Approach to Individualized Therapy in Early Development

Todd M. Pitts, Aik Choon Tan, Gillian N. Kulikowski, John J. Tentler, Amy M. Brown, Sara A. Flanigan, Stephen Leong, Christopher D. Coldren, Fred R. Hirsch, Marileila Varella-Garcia, Christopher Korch and S. Gail Eckhardt

Clin Cancer Res June 15 2010 16 (12) 3193-3204; DOI:10.1158/1078-0432.CCR-09-3191
Cancer Therapy: Preclinical

Molecular Imaging of N-linked Glycosylation Suggests Glycan Biosynthesis Is a Novel Target for Cancer Therapy

Joseph N. Contessa, Mahaveer S. Bhojani, Hudson H. Freeze, Brian D. Ross, Alnawaz Rehemtulla and Theodore S. Lawrence

Clin Cancer Res June 15 2010 16 (12) 3205-3214; DOI:10.1158/1078-0432.CCR-09-3331

Imaging, Diagnosis, Prognosis

Imaging, Diagnosis, Prognosis | Free Article

Drug-Induced Vessel Remodeling in Bone Metastases as Assessed by Dynamic Contrast Enhanced Magnetic Resonance Imaging and Vessel Size Imaging: A Longitudinal In vivo Study

Tobias Bäuerle, Maximilian Merz, Dorde Komljenovic, Stefan Zwick and Wolfhard Semmler

Clin Cancer Res June 15 2010 16 (12) 3215-3225; DOI:10.1158/1078-0432.CCR-09-2932
Imaging, Diagnosis, Prognosis

Complement Factor H Autoantibodies Are Associated with Early Stage NSCLC

Nita Amornsiripanitch, Shaolin Hong, Michael J. Campa, Michael M. Frank, Elizabeth B. Gottlin and Edward F. Patz Jr.

Clin Cancer Res June 15 2010 16 (12) 3226-3231; DOI:10.1158/1078-0432.CCR-10-0321
Imaging, Diagnosis, Prognosis

A Four-Kallikrein Panel Predicts Prostate Cancer in Men with Recent Screening: Data from the European Randomized Study of Screening for Prostate Cancer, Rotterdam

Andrew J. Vickers, Angel M. Cronin, Monique J. Roobol, Caroline J. Savage, Mari Peltola, Kim Pettersson, Peter T. Scardino, Fritz H. Schröder and Hans Lilja

Clin Cancer Res June 15 2010 16 (12) 3232-3239; DOI:10.1158/1078-0432.CCR-10-0122
Imaging, Diagnosis, Prognosis

HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth

Till Milde, Ina Oehme, Andrey Korshunov, Annette Kopp-Schneider, Marc Remke, Paul Northcott, Hedwig E. Deubzer, Marco Lodrini, Michael D. Taylor, Andreas von Deimling, Stefan Pfister and Olaf Witt

Clin Cancer Res June 15 2010 16 (12) 3240-3252; DOI:10.1158/1078-0432.CCR-10-0395
Imaging, Diagnosis, Prognosis

Overexpression of p73 as a Tissue Marker for High-Risk Gastritis

Gonzalo Carrasco, Jose Diaz, Jose R. Valbuena, Paulina Ibanez, Paz Rodriguez, Gabriela Araya, Carolina Rodriguez, Javiera Torres, Ignacio Duarte, Edmundo Aravena, Fernando Mena, Carlos Barrientos and Alejandro H. Corvalan

Clin Cancer Res June 15 2010 16 (12) 3253-3259; DOI:10.1158/1078-0432.CCR-09-2491

Cancer Therapy: Clinical

Cancer Therapy: Clinical

Phase II Clinical and Pharmacokinetic Study of Plitidepsin 3-Hour Infusion Every Two Weeks Alone or with Dexamethasone in Relapsed and Refractory Multiple Myeloma

María Victoria Mateos, Maria Teresa Cibeira, Paul G. Richardson, Felipe Prosper, Albert Oriol, Javier de la Rubia, Juan José Lahuerta, Ramón García-Sanz, Sonia Extremera, Sergio Szyldergemajn, Claudia Corrado, Harald Singer, Constantine S. Mitsiades, Kenneth C. Anderson, Joan Bladé and Jesús San Miguel

Clin Cancer Res June 15 2010 16 (12) 3260-3269; DOI:10.1158/1078-0432.CCR-10-0469
Cancer Therapy: Clinical

Biobehavioral, Immune, and Health Benefits following Recurrence for Psychological Intervention Participants

Barbara L. Andersen, Lisa M. Thornton, Charles L. Shapiro, William B. Farrar, Bethany L. Mundy, Hae-Chung Yang and William E. Carson III

Clin Cancer Res June 15 2010 16 (12) 3270-3278; DOI:10.1158/1078-0432.CCR-10-0278
Cancer Therapy: Clinical

AdCD40L Immunogene Therapy for Bladder Carcinoma—The First Phase I/IIa Trial

Per-Uno Malmström, Angelica S.I. Loskog, Camilla A. Lindqvist, Sara M. Mangsbo, Moa Fransson, Alkwin Wanders, Truls Gårdmark and Thomas H. Tötterman

Clin Cancer Res June 15 2010 16 (12) 3279-3287; DOI:10.1158/1078-0432.CCR-10-0385
Cancer Therapy: Clinical

Imatinib Mesylate as a Preoperative Therapy in Dermatofibrosarcoma: Results of a Multicenter Phase II Study on 25 Patients

Delphine Kérob, Raphael Porcher, Olivier Vérola, Stephane Dalle, Eve Maubec, François Aubin, Michel D'Incan, Isaak Bodokh, Serge Boulinguez, Isabelle Madelaine-Chambrin, Anne Mathieu-Boue, Jean-Marie Servant, Eric de Kerviler, Anne Janin, Fabien Calvo, Florence Pedeutour and Celeste Lebbe

Clin Cancer Res June 15 2010 16 (12) 3288-3295; DOI:10.1158/1078-0432.CCR-09-3401

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Highlights

CCR Translations

Molecular Pathways

CCR Focus

Human Cancer Biology

Cancer Therapy: Preclinical

Imaging, Diagnosis, Prognosis

Cancer Therapy: Clinical

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