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Clinical Cancer Research
Clinical Cancer Research
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About the Cover

Cover image

Cover image expansion

DLL4 is expressed by pericytes/vascular smooth muscle cells in Ewing's sarcoma and was found to be important for formation of the perivascular cell layer. For this image, subcutaneous Ewing's sarcoma tumors from nude mice were harvested and examined by immunohistochemistry for DLL4 (green) and the pericyte/vascular smooth muscle cell marker α-SMA (red). DLL4, α-SMA double positive cells are yellow or orange. Hoescht 33342 was used to visualize nuclei (blue). For details, see the article by Schadler and colleagues on page 848 of this issue.

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Clinical Cancer Research: 16 (3)
February 2010
Volume 16, Issue 3
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Issue Highlights

  • Targeting Vascular Endothelial Growth Factor Receptor in Thyroid Cancer: The Intracellular and Extracellular Implications
  • Antitumor Activity of Targeting Src Kinases in Endothelial and Myeloid Cell Compartments of the Tumor Microenvironment
  • Clinical and Translational Studies of a Phase II Trial of the Novel Oral Akt Inhibitor Perifosine in Relapsed or Relapsed/Refractory Waldenström's Macroglobulinemia
  • Delta-Like Ligand 4 Plays a Critical Role in Pericyte/Vascular Smooth Muscle Cell Formation during Vasculogenesis and Tumor Vessel Expansion in Ewing's Sarcoma
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Clinical Cancer Research
eISSN: 1557-3265
ISSN: 1078-0432

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