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Cancer Therapy: Clinical

Disease Flare after Tyrosine Kinase Inhibitor Discontinuation in Patients with EGFR-Mutant Lung Cancer and Acquired Resistance to Erlotinib or Gefitinib: Implications for Clinical Trial Design

Jamie E. Chaft, Geoffrey R. Oxnard, Camelia S. Sima, Mark G. Kris, Vincent A. Miller and Gregory J. Riely
Jamie E. Chaft
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Geoffrey R. Oxnard
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Camelia S. Sima
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Mark G. Kris
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Vincent A. Miller
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Gregory J. Riely
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DOI: 10.1158/1078-0432.CCR-11-1468 Published October 2011
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Article Information

Volume 17, Issue 19, pp. 6298-6303

DOI 
https://doi.org/10.1158/1078-0432.CCR-11-1468
PubMed 
21856766

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Received June 9, 2011
  • Revision received August 2, 2011
  • Accepted August 11, 2011
  • Published first August 19, 2011.

Article Versions

  • Previous version (August 19, 2011 - 06:38).
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©2011 American Association for Cancer Research.

Author Information

  1. Jamie E. Chaft,
  2. Geoffrey R. Oxnard,
  3. Camelia S. Sima,
  4. Mark G. Kris,
  5. Vincent A. Miller, and
  6. Gregory J. Riely
  1. Authors' Affiliation: Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan-Kettering Cancer Center, Weill Cornell Medical College, New York, New York
  1. Corresponding Author:
    Gregory J. Riely, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10065. Phone: 212-639-3042; Fax: 212-794-4357; E-mail: rielyg{at}mskcc.org
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Clinical Cancer Research: 17 (19)
October 2011
Volume 17, Issue 19
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Disease Flare after Tyrosine Kinase Inhibitor Discontinuation in Patients with EGFR-Mutant Lung Cancer and Acquired Resistance to Erlotinib or Gefitinib: Implications for Clinical Trial Design
Jamie E. Chaft, Geoffrey R. Oxnard, Camelia S. Sima, Mark G. Kris, Vincent A. Miller and Gregory J. Riely
Clin Cancer Res October 1 2011 (17) (19) 6298-6303; DOI: 10.1158/1078-0432.CCR-11-1468

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Disease Flare after Tyrosine Kinase Inhibitor Discontinuation in Patients with EGFR-Mutant Lung Cancer and Acquired Resistance to Erlotinib or Gefitinib: Implications for Clinical Trial Design
Jamie E. Chaft, Geoffrey R. Oxnard, Camelia S. Sima, Mark G. Kris, Vincent A. Miller and Gregory J. Riely
Clin Cancer Res October 1 2011 (17) (19) 6298-6303; DOI: 10.1158/1078-0432.CCR-11-1468
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