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Clinical Cancer Research

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Table of Contents

Highlights

  • Highlights
    Highlights of This Issue
    Clin Cancer Res November 15 2011 17 (22) 6953-6953;

CCR Translations

  • CCR Translations
    MAGE: The Spell Is Broken
    Katayoun Rezvani
    Clin Cancer Res November 15 2011 17 (22) 6955-6957; DOI:10.1158/1078-0432.CCR-11-2302

CCR Drug Updates

  • CCR Drug Updates
    Ipilimumab: An Anti-CTLA-4 Antibody for Metastatic Melanoma
    Evan J. Lipson and Charles G. Drake
    Clin Cancer Res November 15 2011 17 (22) 6958-6962; DOI:10.1158/1078-0432.CCR-11-1595

Molecular Pathways

  • Molecular Pathways
    Novel Insights into the Role of Interleukin-27 and Interleukin-23 in Human Malignant and Normal Plasma Cells
    Nicola Giuliani and Irma Airoldi
    Clin Cancer Res November 15 2011 17 (22) 6963-6970; DOI:10.1158/1078-0432.CCR-11-1724

Perspective

  • Perspective
    DNA Cytometry Testing for Cervical Cancer Screening: Approaches and Reporting Standards for New Technologies
    Graham A. Colditz and John Crowley
    Clin Cancer Res November 15 2011 17 (22) 6971-6972; DOI:10.1158/1078-0432.CCR-11-1862

Reviews

  • Reviews
    DNA Repair: From Genome Maintenance to Biomarker and Therapeutic Target
    Shadia Jalal, Jennifer N. Earley and John J. Turchi
    Clin Cancer Res November 15 2011 17 (22) 6973-6984; DOI:10.1158/1078-0432.CCR-11-0761

  • Reviews
    Indoleamine 2,3-Dioxygenase Expression in Human Cancers: Clinical and Immunologic Perspectives
    Jessica Godin-Ethier, Laïla-Aïcha Hanafi, Ciriaco A. Piccirillo and Réjean Lapointe
    Clin Cancer Res November 15 2011 17 (22) 6985-6991; DOI:10.1158/1078-0432.CCR-11-1331

Human Cancer Biology

  • Human Cancer Biology | Free Article
    Neutrophil Degranulation and Immunosuppression in Patients with GBM: Restoration of Cellular Immune Function by Targeting Arginase I
    Trisha R. Sippel, Jason White, Kamalika Nag, Vadim Tsvankin, Marci Klaassen, B.K. Kleinschmidt-DeMasters and Allen Waziri
    Clin Cancer Res November 15 2011 17 (22) 6992-7002; DOI:10.1158/1078-0432.CCR-11-1107

  • Human Cancer Biology
    Novel Chromosomal Rearrangements and Break Points at the t(6;9) in Salivary Adenoid Cystic Carcinoma: Association with MYB–NFIB Chimeric Fusion, MYB Expression, and Clinical Outcome
    Yoshitsugu Mitani, Pulivarthi H. Rao, P. Andrew Futreal, Dianna B. Roberts, Philip J. Stephens, Yi-Jue Zhao, Li Zhang, Mutsumi Mitani, Randal S. Weber, Scott M. Lippman, Carlos Caulin and Adel K. El-Naggar
    Clin Cancer Res November 15 2011 17 (22) 7003-7014; DOI:10.1158/1078-0432.CCR-11-1870

  • Human Cancer Biology
    Mast Cells in Tumor Microenvironment Promotes the In Vivo Growth of Pancreatic Ductal Adenocarcinoma
    David Z. Chang, Ying Ma, Baoan Ji, Huamin Wang, Defeng Deng, Yan Liu, James L. Abbruzzese, Yong-jun Liu, Craig D. Logsdon and Patrick Hwu
    Clin Cancer Res November 15 2011 17 (22) 7015-7023; DOI:10.1158/1078-0432.CCR-11-0607

  • Human Cancer Biology
    Two Distinct Routes to Oral Cancer Differing in Genome Instability and Risk for Cervical Node Metastasis
    Aditi Bhattacharya, Ritu Roy, Antoine M. Snijders, Gregory Hamilton, Jesse Paquette, Taku Tokuyasu, Henrik Bengtsson, Richard C. K. Jordan, Adam B. Olshen, Daniel Pinkel, Brian L. Schmidt and Donna G. Albertson
    Clin Cancer Res November 15 2011 17 (22) 7024-7034; DOI:10.1158/1078-0432.CCR-11-1944

  • Human Cancer Biology
    Serum Galectin-2, -4, and -8 Are Greatly Increased in Colon and Breast Cancer Patients and Promote Cancer Cell Adhesion to Blood Vascular Endothelium
    Hannah Barrow, Xiuli Guo, Hans H. Wandall, Johannes W. Pedersen, Bo Fu, Qicheng Zhao, Chen Chen, Jonathan M. Rhodes and Lu-Gang Yu
    Clin Cancer Res November 15 2011 17 (22) 7035-7046; DOI:10.1158/1078-0432.CCR-11-1462

Cancer Therapy: Preclinical

  • Cancer Therapy: Preclinical
    Tumor-Derived Autophagosome Vaccine: Mechanism of Cross-Presentation and Therapeutic Efficacy
    Yuhuan Li, Li-Xin Wang, Puiyi Pang, Zhihua Cui, Sandra Aung, Daniel Haley, Bernard A. Fox, Walter J. Urba and Hong-Ming Hu
    Clin Cancer Res November 15 2011 17 (22) 7047-7057; DOI:10.1158/1078-0432.CCR-11-0951

  • Cancer Therapy: Preclinical
    Improving T-cell Therapy for Relapsed EBV-Negative Hodgkin Lymphoma by Targeting Upregulated MAGE-A4
    Conrad R. Cruz, Ulrike Gerdemann, Ann M. Leen, Jessica A. Shafer, Stephanie Ku, Benjamin Tzou, Terzah M. Horton, Andrea Sheehan, Amanda Copeland, Anas Younes, Cliona M. Rooney, Helen E. Heslop and Catherine M. Bollard
    Clin Cancer Res November 15 2011 17 (22) 7058-7066; DOI:10.1158/1078-0432.CCR-11-1873

  • Cancer Therapy: Preclinical
    Therapeutic Implications for the Induced Levels of Chk1 in Myc-Expressing Cancer Cells
    Andreas Höglund, Lisa M. Nilsson, Somsundar Veppil Muralidharan, Lisa A. Hasvold, Philip Merta, Martina Rudelius, Viktoriya Nikolova, Ulrich Keller and Jonas A. Nilsson
    Clin Cancer Res November 15 2011 17 (22) 7067-7079; DOI:10.1158/1078-0432.CCR-11-1198

  • Cancer Therapy: Preclinical
    Glutamatergic Pathway Targeting in Melanoma: Single-Agent and Combinatorial Therapies
    Hwa Jin Lee, Brian A. Wall, Janet Wangari-Talbot, Seung-Shick Shin, Stephen Rosenberg, Joseph L-K. Chan, Jin Namkoong, James S. Goydos and Suzie Chen
    Clin Cancer Res November 15 2011 17 (22) 7080-7092; DOI:10.1158/1078-0432.CCR-11-0098

  • Cancer Therapy: Preclinical
    Synergistic Activity of Fenretinide and the Bcl-2 Family Protein Inhibitor ABT-737 against Human Neuroblastoma
    Hua Fang, Theresa M. Harned, Ondrej Kalous, Vanessa Maldonado, Yves A. DeClerck and C. Patrick Reynolds
    Clin Cancer Res November 15 2011 17 (22) 7093-7104; DOI:10.1158/1078-0432.CCR-11-0578

  • Cancer Therapy: Preclinical
    Reduced miR-128 in Breast Tumor–Initiating Cells Induces Chemotherapeutic Resistance via Bmi-1 and ABCC5
    Yinghua Zhu, Fengyan Yu, Yu Jiao, Juan Feng, Wei Tang, Herui Yao, Chang Gong, Jianing Chen, Fengxi Su, Yan Zhang and Erwei Song
    Clin Cancer Res November 15 2011 17 (22) 7105-7115; DOI:10.1158/1078-0432.CCR-11-0071

  • Cancer Therapy: Preclinical
    Novel Phosphoinositide 3-Kinase/mTOR Dual Inhibitor, NVP-BGT226, Displays Potent Growth-Inhibitory Activity against Human Head and Neck Cancer Cells In Vitro and In Vivo
    Kwang-Yu Chang, Shan-Yin Tsai, Ching-Ming Wu, Chia-Jui Yen, Bin-Fay Chuang and Jang-Yang Chang
    Clin Cancer Res November 15 2011 17 (22) 7116-7126; DOI:10.1158/1078-0432.CCR-11-0796

  • Cancer Therapy: Preclinical
    A Novel Kinase Inhibitor, INCB28060, Blocks c-MET–Dependent Signaling, Neoplastic Activities, and Cross-Talk with EGFR and HER-3
    Xiangdong Liu, Qian Wang, Gengjie Yang, Cindy Marando, Holly K. Koblish, Leslie M. Hall, Jordan S. Fridman, Elham Behshad, Richard Wynn, Yu Li, Jason Boer, Sharon Diamond, Chunhong He, Meizhong Xu, Jincong Zhuo, Wenqing Yao, Robert C. Newton and Peggy A. Scherle
    Clin Cancer Res November 15 2011 17 (22) 7127-7138; DOI:10.1158/1078-0432.CCR-11-1157

Imaging, Diagnosis, Prognosis

  • Imaging, Diagnosis, Prognosis
    Genetic Variation in Inflammatory Pathways Is Related to Colorectal Cancer Survival
    Anna E. Coghill, Polly A. Newcomb, Elizabeth M. Poole, Carolyn M. Hutter, Karen W. Makar, Dave Duggan, John D. Potter and Cornelia M. Ulrich
    Clin Cancer Res November 15 2011 17 (22) 7139-7147; DOI:10.1158/1078-0432.CCR-11-1134

  • Imaging, Diagnosis, Prognosis
    A Hypermethylated Phenotype Is a Better Predictor of Survival than MGMT Methylation in Anaplastic Oligodendroglial Brain Tumors: A Report from EORTC Study 26951
    Martin J. van den Bent, Lonneke A. Gravendeel, Thierry Gorlia, Johan M. Kros, Lariesa Lapre, Pieter Wesseling, Johannes L. Teepen, Ahmed Idbaih, Marc Sanson, Peter A.E. Sillevis Smitt and Pim J. French
    Clin Cancer Res November 15 2011 17 (22) 7148-7155; DOI:10.1158/1078-0432.CCR-11-1274

Cancer Therapy: Clinical

  • Cancer Therapy: Clinical
    Biologic and Clinical Activity of Tivozanib (AV-951, KRN-951), a Selective Inhibitor of VEGF Receptor-1, -2, and -3 Tyrosine Kinases, in a 4-Week-On, 2-Week-Off Schedule in Patients with Advanced Solid Tumors
    Ferry A.L.M. Eskens, Maja J.A. de Jonge, Pankaj Bhargava, Toshiyuki Isoe, Monette M. Cotreau, Brooke Esteves, Kunihiko Hayashi, Herman Burger, Maarten Thomeer, Leni van Doorn and Jaap Verweij
    Clin Cancer Res November 15 2011 17 (22) 7156-7163; DOI:10.1158/1078-0432.CCR-11-0411

  • Cancer Therapy: Clinical
    A Pilot Study of MUC-1/CEA/TRICOM Poxviral-Based Vaccine in Patients with Metastatic Breast and Ovarian Cancer
    Mahsa Mohebtash, Kwong-Yok Tsang, Ravi A. Madan, Ngar-Yee Huen, Diane J. Poole, Caroline Jochems, Jacquin Jones, Theresa Ferrara, Christopher R. Heery, Philip M. Arlen, Seth M. Steinberg, Mary Pazdur, Myrna Rauckhorst, Elizabeth C. Jones, William L. Dahut, Jeffrey Schlom and James L. Gulley
    Clin Cancer Res November 15 2011 17 (22) 7164-7173; DOI:10.1158/1078-0432.CCR-11-0649

  • Cancer Therapy: Clinical
    GLIPR1 Tumor Suppressor Gene Expressed by Adenoviral Vector as Neoadjuvant Intraprostatic Injection for Localized Intermediate or High-Risk Prostate Cancer Preceding Radical Prostatectomy
    Guru Sonpavde, Timothy C. Thompson, Rajul K. Jain, Gustavo E. Ayala, Shinji Kurosaka, Kohei Edamura, Ken-ichi Tabata, Chengzhen Ren, Alexei A. Goltsov, Martha P. Mims, Teresa G. Hayes, Michael M. Ittmann, Thomas M. Wheeler, Adrian Gee, Brian J. Miles and Dov Kadmon
    Clin Cancer Res November 15 2011 17 (22) 7174-7182; DOI:10.1158/1078-0432.CCR-11-1899

Predictive Biomarkers and Personalized Medicine

  • Predictive Biomarkers and Personalized Medicine
    Cytokeratin-19 and Mammaglobin Gene Expression in Circulating Tumor Cells from Metastatic Breast Cancer Patients Enrolled in North Central Cancer Treatment Group Trials, N0234/336/436/437
    Monica M. Reinholz, Kathleen A. Kitzmann, Kathleen Tenner, David Hillman, Amylou C. Dueck, Timothy J. Hobday, Donald W. Northfelt, Alvaro Moreno-Aspitia, Vivek Roy, Betsy LaPlant, Jake B. Allred, Philip J. Stella, Wilma L. Lingle and Edith A. Perez
    Clin Cancer Res November 15 2011 17 (22) 7183-7193; DOI:10.1158/1078-0432.CCR-11-0981

  • Predictive Biomarkers and Personalized Medicine
    Relationship between Quantitative GRB7 RNA Expression and Recurrence after Adjuvant Anthracycline Chemotherapy in Triple-Negative Breast Cancer
    Joseph A. Sparano, Lori J. Goldstein, Barrett H. Childs, Steven Shak, Diana Brassard, Sunil Badve, Frederick L. Baehner, Roberto Bugarini, Steve Rowley, Edith A. Perez, Lawrence N. Shulman, Silvana Martino, Nancy E. Davidson, Paraic A. Kenny, George W. Sledge Jr and Robert Gray
    Clin Cancer Res November 15 2011 17 (22) 7194-7203; DOI:10.1158/1078-0432.CCR-10-3357

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Clinical Cancer Research: 17 (22)
November 2011
Volume 17, Issue 22
  • Table of Contents
  • Table of Contents (PDF)
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Issue Highlights

  • Glutamatergic Pathway Targeting in Melanoma: Single-Agent and Combinatorial Therapies
  • Neutrophil Degranulation and Immunosuppression in Patients with GBM: Restoration of Cellular Immune Function by Targeting Arginase I
  • Serum Galectin-2, -4, and -8 Are Greatly Increased in Colon and Breast Cancer Patients and Promote Cancer Cell Adhesion to Blood Vascular Endothelium
  • Reduced miR-128 in Breast Tumor–Initiating Cells Induces Chemotherapeutic Resistance via Bmi-1 and ABCC5
  • A Novel Kinase Inhibitor, INCB28060, Blocks c-MET–Dependent Signaling, Neoplastic Activities, and Cross-Talk with EGFR and HER-3

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Clinical Cancer Research
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