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Clinical Cancer Research
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Predictive Biomarkers and Personalized Medicine

Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in EGFR-Mutant Lung Cancer: Distinct Natural History of Patients with Tumors Harboring the T790M Mutation

Geoffrey R. Oxnard, Maria E. Arcila, Camelia S. Sima, Gregory J. Riely, Juliann Chmielecki, Mark G. Kris, William Pao, Marc Ladanyi and Vincent A. Miller
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Camelia S. Sima
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DOI: 10.1158/1078-0432.CCR-10-2692 Published March 2011
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Article Information

Volume 17, Issue 6, pp. 1616-1622

DOI 
https://doi.org/10.1158/1078-0432.CCR-10-2692
PubMed 
21135146

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Received October 6, 2010
  • Revision received November 19, 2010
  • Accepted November 24, 2010
  • Published first December 6, 2010.

Article Versions

  • Previous version (December 6, 2010 - 09:21).
  • You are viewing the most recent version of this article.
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©2010 American Association for Cancer Research.

Author Information

  1. Geoffrey R. Oxnard1,
  2. Maria E. Arcila2,
  3. Camelia S. Sima3,
  4. Gregory J. Riely1,
  5. Juliann Chmielecki4,
  6. Mark G. Kris1,
  7. William Pao1,4,
  8. Marc Ladanyi2,4, and
  9. Vincent A. Miller1
  1. Authors' Affiliations: 1Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, 2Molecular Diagnostics Service, Department of Pathology, 3Department of Epidemiology and Biostatistics, and 4Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, Weill Medical College of Cornell University, New York
  1. Corresponding Author:
    Vincent A. Miller, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065. Phone: 212-639-7243; Fax: 212-794-4357. E-mail: millerv{at}mskcc.org
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Clinical Cancer Research: 17 (6)
March 2011
Volume 17, Issue 6
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Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in EGFR-Mutant Lung Cancer: Distinct Natural History of Patients with Tumors Harboring the T790M Mutation
Geoffrey R. Oxnard, Maria E. Arcila, Camelia S. Sima, Gregory J. Riely, Juliann Chmielecki, Mark G. Kris, William Pao, Marc Ladanyi and Vincent A. Miller
Clin Cancer Res March 15 2011 (17) (6) 1616-1622; DOI: 10.1158/1078-0432.CCR-10-2692

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Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in EGFR-Mutant Lung Cancer: Distinct Natural History of Patients with Tumors Harboring the T790M Mutation
Geoffrey R. Oxnard, Maria E. Arcila, Camelia S. Sima, Gregory J. Riely, Juliann Chmielecki, Mark G. Kris, William Pao, Marc Ladanyi and Vincent A. Miller
Clin Cancer Res March 15 2011 (17) (6) 1616-1622; DOI: 10.1158/1078-0432.CCR-10-2692
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Clinical Cancer Research
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