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Cancer Therapy: Clinical

Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer

Keith T. Flaherty, Patricia M. LoRusso, Angela DeMichele, Vandana G. Abramson, Rachel Courtney, Sophia S. Randolph, M. Naveed Shaik, Keith D. Wilner, Peter J. O'Dwyer and Gary K. Schwartz
Keith T. Flaherty
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Patricia M. LoRusso
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Angela DeMichele
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Vandana G. Abramson
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Rachel Courtney
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Sophia S. Randolph
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M. Naveed Shaik
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Keith D. Wilner
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Peter J. O'Dwyer
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DOI: 10.1158/1078-0432.CCR-11-0509 Published January 2012
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Article Information

Volume 18, Issue 2, pp. 568-576

DOI 
https://doi.org/10.1158/1078-0432.CCR-11-0509
PubMed 
22090362

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Received March 21, 2011
  • Revision received November 1, 2011
  • Accepted November 6, 2011
  • Published first November 16, 2011.

Article Versions

  • Previous version (November 16, 2011 - 08:42).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2011 American Association for Cancer Research.

Author Information

  1. Keith T. Flaherty1,
  2. Patricia M. LoRusso2,
  3. Angela DeMichele1,
  4. Vandana G. Abramson1,
  5. Rachel Courtney3,
  6. Sophia S. Randolph3,
  7. M. Naveed Shaik3,
  8. Keith D. Wilner3,
  9. Peter J. O'Dwyer1, and
  10. Gary K. Schwartz4
  1. Authors' Affiliations: 1Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania; 2Karmanos Cancer Institute, Detroit, Michigan; 3Pfizer Oncology, San Diego, California; and 4Memorial Sloan-Kettering Cancer Center, New York
  1. Corresponding Author:
    Peter J. O'Dwyer, Abramson Cancer Center, University of Pennsylvania, 16 Penn Tower, 3400 Spruce St., Philadelphia, PA 19104. Phone: 215-662-7606; Fax: 215-349-8551; E-mail: peter.odwyer{at}uphs.upenn.edu
  • Current address for K.T. Flaherty: Massachusetts General Hospital Cancer Center, Boston, MA; and current address for V.G. Abramson: Vanderbilt University School of Medicine, Nashville, TN.

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Clinical Cancer Research: 18 (2)
January 2012
Volume 18, Issue 2
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Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer
Keith T. Flaherty, Patricia M. LoRusso, Angela DeMichele, Vandana G. Abramson, Rachel Courtney, Sophia S. Randolph, M. Naveed Shaik, Keith D. Wilner, Peter J. O'Dwyer and Gary K. Schwartz
Clin Cancer Res January 15 2012 (18) (2) 568-576; DOI: 10.1158/1078-0432.CCR-11-0509

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Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer
Keith T. Flaherty, Patricia M. LoRusso, Angela DeMichele, Vandana G. Abramson, Rachel Courtney, Sophia S. Randolph, M. Naveed Shaik, Keith D. Wilner, Peter J. O'Dwyer and Gary K. Schwartz
Clin Cancer Res January 15 2012 (18) (2) 568-576; DOI: 10.1158/1078-0432.CCR-11-0509
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