Clinical Cancer Research: 19 (12)

Highlights

Highlights

Highlights of This Issue

Clin Cancer Res June 15 2013 19 (12) 3109-3109;

CCR Translations

CCR Translations

Stearoyl Co-A Desaturase 1 as a ccRCC Therapeutic Target: Death by Stress

Janet Y. Leung and William Y. Kim

Clin Cancer Res June 15 2013 19 (12) 3111-3113; DOI:10.1158/1078-0432.CCR-13-0800

Molecular Pathways

Molecular Pathways

Molecular Pathways: Extracting Medical Knowledge from High-Throughput Genomic Data

Theodore C. Goldstein, Evan O. Paull, Matthew J. Ellis and Joshua M. Stuart

Clin Cancer Res June 15 2013 19 (12) 3114-3120; DOI:10.1158/1078-0432.CCR-12-2093

Human Cancer Biology

Human Cancer Biology

microRNA Expression Profiles Identify Subtypes of Mantle Cell Lymphoma with Different Clinicobiological Characteristics

Alba Navarro, Guillem Clot, Miriam Prieto, Cristina Royo, Maria Carmela Vegliante, Virginia Amador, Elena Hartmann, Itziar Salaverria, Sílvia Beà, Jose Ignacio Martín-Subero, Andreas Rosenwald, German Ott, Adrian Wiestner, Wyndham H. Wilson, Elías Campo and Luis Hernández

Clin Cancer Res June 15 2013 19 (12) 3121-3129; DOI:10.1158/1078-0432.CCR-12-3077
Human Cancer Biology

Biological and Clinical Relevance of miRNA Expression Signatures in Primary Plasma Cell Leukemia

Marta Lionetti, Pellegrino Musto, Maria Teresa Di Martino, Sonia Fabris, Luca Agnelli, Katia Todoerti, Giacomo Tuana, Laura Mosca, Maria E. Gallo Cantafio, Vitina Grieco, Gabriella Bianchino, Fiorella D'Auria, Teodora Statuto, Carmela Mazzoccoli, Luciana De Luca, Maria Teresa Petrucci, Massimo Offidani, Francesco Di Raimondo, Antonietta Falcone, Tommaso Caravita, Paola Omede', Fortunato Morabito, Pierfrancesco Tassone, Mario Boccadoro, Antonio Palumbo and Antonino Neri

Clin Cancer Res June 15 2013 19 (12) 3130-3142; DOI:10.1158/1078-0432.CCR-12-2043
Human Cancer Biology

Conjunctival Melanomas Harbor BRAF and NRAS Mutations and Copy Number Changes Similar to Cutaneous and Mucosal Melanomas

Klaus G. Griewank, Henrike Westekemper, Rajmohan Murali, Monika Mach, Bastian Schilling, Thomas Wiesner, Tobias Schimming, Elisabeth Livingstone, Antje Sucker, Florian Grabellus, Claudia Metz, Daniela Süsskind, Uwe Hillen, Michael R. Speicher, Scott E. Woodman, Klaus-Peter Steuhl and Dirk Schadendorf

Clin Cancer Res June 15 2013 19 (12) 3143-3152; DOI:10.1158/1078-0432.CCR-13-0163

Cancer Therapy: Preclinical

Cancer Therapy: Preclinical

Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells

Michael Hudecek, Maria-Teresa Lupo-Stanghellini, Paula L. Kosasih, Daniel Sommermeyer, Michael C. Jensen, Christoph Rader and Stanley R. Riddell

Clin Cancer Res June 15 2013 19 (12) 3153-3164; DOI:10.1158/1078-0432.CCR-13-0330
Cancer Therapy: Preclinical

Gliomas Promote Immunosuppression through Induction of B7-H1 Expression in Tumor-Associated Macrophages

Orin Bloch, Courtney A. Crane, Rajwant Kaur, Michael Safaee, Martin J. Rutkowski and Andrew T. Parsa

Clin Cancer Res June 15 2013 19 (12) 3165-3175; DOI:10.1158/1078-0432.CCR-12-3314
Cancer Therapy: Preclinical

IL-17–Mediated M1/M2 Macrophage Alteration Contributes to Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaws

Qunzhou Zhang, Ikiru Atsuta, Shiyu Liu, Chider Chen, Shihong Shi, Songtao Shi and Anh D. Le

Clin Cancer Res June 15 2013 19 (12) 3176-3188; DOI:10.1158/1078-0432.CCR-13-0042
Cancer Therapy: Preclinical | Free Article

ATM Kinase Inhibition Preferentially Sensitizes p53-Mutant Glioma to Ionizing Radiation

Laura Biddlestone-Thorpe, Muhammad Sajjad, Elizabeth Rosenberg, Jason M. Beckta, Nicholas C.K. Valerie, Mary Tokarz, Bret R. Adams, Alison F. Wagner, Ashraf Khalil, Donna Gilfor, Sarah E. Golding, Sumitra Deb, David G. Temesi, Alan Lau, Mark J. O'Connor, Kevin S. Choe, Luis F. Parada, Sang Kyun Lim, Nitai D. Mukhopadhyay and Kristoffer Valerie

Clin Cancer Res June 15 2013 19 (12) 3189-3200; DOI:10.1158/1078-0432.CCR-12-3408
Cancer Therapy: Preclinical

Frequent Inactivation of Cysteine Dioxygenase Type 1 Contributes to Survival of Breast Cancer Cells and Resistance to Anthracyclines

Jana Jeschke, Heather M. O'Hagan, Wei Zhang, Rajita Vatapalli, Marilia Freitas Calmon, Ludmila Danilova, Claudia Nelkenbrecher, Leander Van Neste, Ingrid T.G.W. Bijsmans, Manon Van Engeland, Edward Gabrielson, Kornel E. Schuebel, Andreas Winterpacht, Stephen B. Baylin, James G. Herman and Nita Ahuja

Clin Cancer Res June 15 2013 19 (12) 3201-3211; DOI:10.1158/1078-0432.CCR-12-3751
Cancer Therapy: Preclinical

Cap-Translation Inhibitor, 4EGI-1, Restores Sensitivity to ABT-737 Apoptosis through Cap-Dependent and -Independent Mechanisms in Chronic Lymphocytic Leukemia

Shaun Willimott, Daniel Beck, Matthew J. Ahearne, Victoria C. Adams and Simon D. Wagner

Clin Cancer Res June 15 2013 19 (12) 3212-3223; DOI:10.1158/1078-0432.CCR-12-2185
Cancer Therapy: Preclinical

Prolonged Inhibition of Glioblastoma Xenograft Initiation and Clonogenic Growth following In Vivo Notch Blockade

Qian Chu, Brent A. Orr, Samantha Semenkow, Eli E. Bar and Charles G. Eberhart

Clin Cancer Res June 15 2013 19 (12) 3224-3233; DOI:10.1158/1078-0432.CCR-12-2119
Cancer Therapy: Preclinical

Monoclonal Antibody against the Ectodomain of E-Cadherin (DECMA-1) Suppresses Breast Carcinogenesis: Involvement of the HER/PI3K/Akt/mTOR and IAP Pathways

Sabine M. Brouxhon, Stephanos Kyrkanides, Xiaofei Teng, Veena Raja, M. Kerry O'Banion, Robert Clarke, Stephen Byers, Andrew Silberfeld, Carmen Tornos and Li Ma

Clin Cancer Res June 15 2013 19 (12) 3234-3246; DOI:10.1158/1078-0432.CCR-12-2747

Imaging, Diagnosis, Prognosis

Imaging, Diagnosis, Prognosis

Transcriptional Characterization of a Prospective Series of Primary Plasma Cell Leukemia Revealed Signatures Associated with Tumor Progression and Poorer Outcome

Katia Todoerti, Luca Agnelli, Sonia Fabris, Marta Lionetti, Giacomo Tuana, Laura Mosca, Luigia Lombardi, Vitina Grieco, Gabriella Bianchino, Fiorella D'Auria, Teodora Statuto, Carmela Mazzoccoli, Luciana De Luca, Maria Teresa Petrucci, Fortunato Morabito, Massimo Offidani, Francesco Di Raimondo, Antonietta Falcone, Paola Omede', Pierfrancesco Tassone, Mario Boccadoro, Antonio Palumbo, Antonino Neri and Pellegrino Musto

Clin Cancer Res June 15 2013 19 (12) 3247-3258; DOI:10.1158/1078-0432.CCR-12-3461
Imaging, Diagnosis, Prognosis

Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network

A. Ari Hakimi, Irina Ostrovnaya, Boris Reva, Nikolaus Schultz, Ying-Bei Chen, Mithat Gonen, Han Liu, Shugaku Takeda, Martin H. Voss, Satish K. Tickoo, Victor E. Reuter, Paul Russo, Emily H. Cheng, Chris Sander, Robert J. Motzer and James J. Hsieh; for The ccRCC Cancer Genome Atlas (KIRC TCGA) Research Network investigators

Clin Cancer Res June 15 2013 19 (12) 3259-3267; DOI:10.1158/1078-0432.CCR-12-3886
Imaging, Diagnosis, Prognosis

EDNRB and DCC Salivary Rinse Hypermethylation Has a Similar Performance as Expert Clinical Examination in Discrimination of Oral Cancer/Dysplasia versus Benign Lesions

Juliana Schussel, Xian Chong Zhou, Zhe Zhang, Kavita Pattani, Francisco Bermudez, Germain Jean-Charles, Thomas McCaffrey, Tapan Padhya, Joan Phelan, Silvia Spivakovsky, Mariana Brait, Ryan Li, Helen Yoo Bowne, Judith D. Goldberg, Linda Rolnitzky, Miriam Robbins, A. Ross Kerr, David Sirois and Joseph A. Califano

Clin Cancer Res June 15 2013 19 (12) 3268-3275; DOI:10.1158/1078-0432.CCR-12-3496
Imaging, Diagnosis, Prognosis

Noninvasive Detection of HER2 Amplification with Plasma DNA Digital PCR

Heidrun Gevensleben, Isaac Garcia-Murillas, Monika K. Graeser, Gaia Schiavon, Peter Osin, Marina Parton, Ian E. Smith, Alan Ashworth and Nicholas C. Turner

Clin Cancer Res June 15 2013 19 (12) 3276-3284; DOI:10.1158/1078-0432.CCR-12-3768
Imaging, Diagnosis, Prognosis

PIK3CA and PTEN Gene and Exon Mutation-Specific Clinicopathologic and Molecular Associations in Colorectal Cancer

Fiona L. Day, Robert N. Jorissen, Lara Lipton, Dmitri Mouradov, Anuratha Sakthianandeswaren, Michael Christie, Shan Li, Cary Tsui, Jeannie Tie, Jayesh Desai, Zheng-Zhou Xu, Peter Molloy, Vicki Whitehall, Barbara A. Leggett, Ian T. Jones, Stephen McLaughlin, Robyn L. Ward, Nicholas J. Hawkins, Andrew R. Ruszkiewicz, James Moore, Dana Busam, Qi Zhao, Robert L. Strausberg, Peter Gibbs and Oliver M. Sieber

Clin Cancer Res June 15 2013 19 (12) 3285-3296; DOI:10.1158/1078-0432.CCR-12-3614

Cancer Therapy: Clinical

Cancer Therapy: Clinical

Prospective Phase II Study on 5-Days Azacitidine for Treatment of Symptomatic and/or Erythropoietin Unresponsive Patients with Low/INT-1–Risk Myelodysplastic Syndromes

Carla Filì, Michele Malagola, Matilde Y. Follo, Carlo Finelli, Ilaria Iacobucci, Giovanni Martinelli, Federica Cattina, Cristina Clissa, Anna Candoni, Renato Fanin, Marco Gobbi, Monica Bocchia, Marzia Defina, Pierangelo Spedini, Cristina Skert, Lucia Manzoli, Lucio Cocco and Domenico Russo

Clin Cancer Res June 15 2013 19 (12) 3297-3308; DOI:10.1158/1078-0432.CCR-12-3540
Cancer Therapy: Clinical

A Review of Study Designs and Outcomes of Phase I Clinical Studies of Nanoparticle Agents Compared with Small-Molecule Anticancer Agents

Whitney P. Caron, Katherine P. Morgan, Beth A. Zamboni and William C. Zamboni

Clin Cancer Res June 15 2013 19 (12) 3309-3315; DOI:10.1158/1078-0432.CCR-12-3649

Predictive Biomarkers and Personalized Medicine

Predictive Biomarkers and Personalized Medicine

CYP3A4*22 Genotype and Systemic Exposure Affect Paclitaxel-Induced Neurotoxicity

Anne-Joy M. de Graan, Laure Elens, Jason A. Sprowl, Alex Sparreboom, Lena E. Friberg, Bronno van der Holt, Pleun J. de Raaf, Peter de Bruijn, Frederike K. Engels, Ferry A.L.M. Eskens, Erik A.C. Wiemer, Jaap Verweij, Ron H.J. Mathijssen and Ron H.N. van Schaik

Clin Cancer Res June 15 2013 19 (12) 3316-3324; DOI:10.1158/1078-0432.CCR-12-3786

Letters to the Editor

Letters to the Editor

Plasma MicroRNAs in Ovarian Cancer—Letter

Haifeng Qiu

Clin Cancer Res June 15 2013 19 (12) 3325-3325; DOI:10.1158/1078-0432.CCR-13-0561
Letters to the Editor

Plasma MicroRNAs in Ovarian Cancer—Response

Xin Huang and Anda M. Vlad

Clin Cancer Res June 15 2013 19 (12) 3326-3326; DOI:10.1158/1078-0432.CCR-13-1022

Retraction

Retraction

Retraction: Functional Characterization of the Bladder Cancer Marker, BLCA-4

Clin Cancer Res June 15 2013 19 (12) 3327-3327; DOI:10.1158/1078-0432.CCR-13-1145

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Table of Contents

Highlights

CCR Translations

Molecular Pathways

Human Cancer Biology

Cancer Therapy: Preclinical

Imaging, Diagnosis, Prognosis

Cancer Therapy: Clinical

Predictive Biomarkers and Personalized Medicine

Letters to the Editor

Retraction

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